Evidence map›Paper›PMID 35149855›Full record

ArticleBritish journal of cancer2022

Socio-economic inequalities in cancer survival: how do they translate into Number of Life-Years Lost?

Aimilia Exarchakou, Dimitra-Kleio Kipourou, Aurélien Belot, Bernard Rachet

2 registry-linked trialsAbstract read
In one paragraph

Article in British journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07007169 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Mediterranean Diet and Inequality in Early Breast Cancer: A Multicenter Randomized Clinical Trial

TypeinterventionalSponsorEsbjerg Hospital - University Hospital of Southern DenmarkRan2025 to 2036Enrolled105ConditionsEarly Breast CancerArmsThe goal is daily consumption of a minimum of 30 grams of dietary fiber and weekly consumption of a minimum of 30 different plant foods, minimizing the amount of ultra-processed food., Standard Diet
NCT07553481 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Chemotherapy-Induced Hearing Loss and Health Inequality

TypeobservationalSponsorLancaster UniversityRan2026 to 2028Enrolled172ConditionsCancer, Chemo Brain, Chemotherapy, Hearing
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Low income and health literacy: a systematic scoping review.Archives of public health = Archives belges de sante publique · 2025
    Pooled it
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  11. Peptide-Drug Conjugates: A New Hope for Cancer.Journal of peptide science : an official publication of the European Peptide Society · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aimilia ExarchakouInequalities in Cancer Outcomes Network (ICON), Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. Aimilia.Exarchakou@lshtm.ac.uk.ORCID http://orcid.org/0000-0003-4881-6183
Dimitra-Kleio KipourouInequalities in Cancer Outcomes Network (ICON), Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Aurélien BelotInequalities in Cancer Outcomes Network (ICON), Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.ORCID http://orcid.org/0000-0003-1410-5172
Bernard RachetInequalities in Cancer Outcomes Network (ICON), Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.

Funding

Cancer Research UK 18525Cancer Research UK 29018
6 · The paper itself

Abstract

backgroundWe aimed to investigate the impact of socio-economic inequalities in cancer survival in England on the Number of Life-Years Lost (NLYL) due to cancer.

methodsWe analysed 1.2 million patients diagnosed with one of the 23 most common cancers (92.3% of all incident cancers in England) between 2010 and 2014. Socio-economic deprivation of patients was based on the income domain of the English Index of Deprivation. We estimated the NLYL due to cancer within 3 years since diagnosis for each cancer and stratified by sex, age and deprivation, using a non-parametric approach. The relative survival framework enables us to disentangle death from cancer and death from other causes without the information on the cause of death.

resultsThe largest socio-economic inequalities were seen mostly in adults <45 years with poor-prognosis cancers. In this age group, the most deprived patients with lung, pancreatic and oesophageal cancer lost up to 6 additional months within 3 years since diagnosis than the least deprived. For most moderate/good prognosis cancers, the socio-economic inequalities widened with age.

conclusionsMore deprived patients and particularly the young with more lethal cancers, lose systematically more life-years than the less deprived. To reduce these inequalities, cancer policies should systematically encompass the inequities component.

Indexed as

NeoplasmsAdultEnglandHumansInfantSocioeconomic Factors

Identifiers

PMID35149855
PMCPMC9090931

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.