ArticlePediatric research2022
Infective endocarditis in children and adolescents: a different profile with clinical implications.
Article in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Infective endocarditis in the pediatric population: A single-center retrospective study of outcomes and predictors.European journal of pediatrics · 2026Article
- Transthoracic echocardiography in children withBMJ paediatrics open · 2026Article
- Clinical Features and Outcomes of Surgically Treated Infective Endocarditis in Adults with and Without Congenital Heart Disease: A 12-Year Cohort Study.Journal of cardiovascular development and disease · 2026Article
- Article
- Analysis of the International, Regional, and National Endocarditis-Related Disease Burdens (1990-2021), and Changes to Projections for the Next 15 Years: A Population-Based Study.Reviews in cardiovascular medicine · 2025Article
- The prognostic role of vegetation size in pediatric infective endocarditis: a retrospective study using decision curve and dose-response analysis.BMC infectious diseases · 2025Article
- Clinical features of intracardiac thrombotic complication in patients with severe Mycoplasma pneumoniae pneumonia.Italian journal of pediatrics · 2025Article
- Burden and trend of cardiovascular diseases in youths aged 0-19 years in China, Asia, and the world, with forecasts to 2036: a systematic analysis of the global burden of disease study 2021.Frontiers in public health · 2025Article
- Infective Endocarditis at a Referral Children's Hospital During 19-Year Period: Trends and Outcomes.Pediatric cardiology · 2024Article
- Right-sided infective endocarditis or thrombus? Report of two cases diagnosed by transthoracic echocardiography.Journal of cardiothoracic surgery · 2024Article
- Surgery for Infective Endocarditis with Aortic Valve Damage in Children: A Case Report and Literature Review.Journal of inflammation research · 2024Article
- The Role of Multimodality Imaging in Patients with Congenital Heart Disease and Infective Endocarditis.Diagnostics (Basel, Switzerland) · 2023Review
- Epidemiology, Diagnosis, Treatment, and Prognosis of Infective Endocarditis.Journal of clinical medicine · 2023Article
- Infective Endocarditis among Pediatric Patients with Prosthetic Valves and Cardiac Devices: A Review and Update of Recent Emerging Diagnostic and Management Strategies.Journal of clinical medicine · 2023Review
- Article
- Epidemiological, Bacteriological, and Evolutive Features of Children Hospitalized for Infective Endocarditis in a Tertiary Tunisian Pediatric Department.Journal of the Saudi Heart Association · 2023Article
- Pediatric Infective Endocarditis: A Literature Review.Journal of clinical medicine · 2022Review
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Authors and funding
15 authors at 12 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur aim was to compare pediatric infective endocarditis (IE) with the clinical profile and outcomes of IE in adults.
methodsProspective multicenter registry in 31 Spanish hospitals including all patients with a diagnosis of IE from 2008 to 2020.
resultsA total of 5590 patients were included, 49 were <18 years (0.1%). Congenital heart disease (CHD) was present in 31 children and adolescents (63.2%). Right-sided location was more common in children/adolescents than in adults (46.9% vs. 6.3%, P < 0.001). Pediatric pulmonary IE was more frequent in patients with CHD (48.4%) than in those without (5.6%), P = 0.004. Staphylococcus aureus etiology tended to be more common in pediatric patients (32.7%) than in adults (22.3%), P = 0.082. Heart failure was less common in pediatric patients than in adults, due to the lower rate of heart failure in children/adolescents with CHD (9.6%) with respect to those without CHD (44.4%), P = 0.005. Inhospital mortality was high in both children, and adolescents and adults (16.3% vs. 25.9%; P = 0.126).
conclusionsMost IE cases in children and adolescents are seen in patients with CHD that have a more common right-sided location and a lower prevalence of heart failure than patients without CHD. IE in children and adolescents without CHD has a more similar profile to IE in adults. IMPACT: Infective endocarditis (IE) in children and adolescents is often seen in patients with congenital heart disease (CHD). Right-sided location is the most common in patients with CHD and heart failure is less common as a complication compared with patients without CHD. Infective endocarditis (IE) in children/adolescents without CHD has a more similar profile to IE in adults. In children/adolescents without CHD, locations were similar to adults, including a predominance of left-sided IE. Acute heart failure was the most frequent complication, seen mainly in adults, and in children/adolescents without CHD.
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