Evidence map›Paper›PMID 35149710›Full record

ArticleScientific reports2022

Comprehensive assessment of systemic arteriosclerosis in relation to the ocular resistive index in acute coronary syndrome patients.

Yasunari Ebuchi, Taiji Nagaoka, Daisuke Fukamachi, Keisuke Kojima, Naotaka Akutsu, Nobuhiro Murata, Yuki Saito, Daisuke Kitano, Harumasa Yokota, Satoru Yamagami and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yasunari EbuchiDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Taiji NagaokaDivision of Ophthalmology, Nihon University Itabashi Hospital, Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan. taijinagaoka@gmail.com.
Daisuke FukamachiDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Keisuke KojimaDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Naotaka AkutsuDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Nobuhiro MurataDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Yuki SaitoDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Daisuke KitanoDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Harumasa YokotaDivision of Ophthalmology, Nihon University Itabashi Hospital, Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.
Satoru YamagamiDivision of Ophthalmology, Nihon University Itabashi Hospital, Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.
Yasuo OkumuraDivision of Cardiology, Nihon University Itabashi Hospital, Tokyo, Japan.
Nihon University Itabashi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the relationship between ocular vascular resistance parameters, evaluated by laser speckle flowgraphy (LSFG), and systemic atherosclerosis, renal parameters and cardiac function in acute coronary syndrome (ACS) patients. We evaluated 53 ACS patients between April 2019 and September 2020. LSFG measured the mean blur rate (MBR) and ocular blowout time (BOT) and resistivity index (RI). 110 consequent patients without a history of coronary artery disease who visited ophthalmology as a control group. Significant positive correlations were observed between ocular RI and systemic parameters in ACS patients, including intima-media thickness (r = 0.34, P = 0.015), brachial-ankle pulse-wave velocity (r = 0.41, P = 0.002), cystatin C (r = 0.32, P = 0.020), and E/e' (r = 0.34, P = 0.013). Ocular RI was significantly higher in the ACS group than in the control group in male in their 40 s (0.37 ± 0.02 vs. 0.29 ± 0.01, P < 0.001) and 50 s (0.36 ± 0.02 vs. 0.30 ± 0.01, P = 0.01). We found that the ocular RI was associated with systemic atherosclerosis, early renal dysfunction, and diastolic cardiac dysfunction in ACS patients, suggesting that it could be a useful non-invasive comprehensive arteriosclerotic marker.

Indexed as

Vascular ResistanceAcute Coronary SyndromeAgedAtherosclerosisBiomarkersCarotid Intima-Media ThicknessEchocardiographyEyeFemaleHumansKidney Function TestsLaser Speckle Contrast ImagingMaleMiddle AgedRetinal DiseasesBiomarkers

Identifiers

PMID35149710
PMCPMC8837772
OpenAlexW4211140939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.