ArticleDevelopmental cell2022
Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense.
Article in Developmental cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 72 citations in OpenAlex.
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- Histone deacetylases and cell-cycle regulators orchestrate cell-identity transitions during Arabidopsis root regeneration.Molecular plant · 2026Article
- Natural Elicitor 3,4-Dihydroxy-3-Methyl-2-Pentanone Induces Disease Resistance inPlants (Basel, Switzerland) · 2026Article
- EnhancedPlants (Basel, Switzerland) · 2025Article
- A maize mutant in the glutamate receptor-like dwarf13 is modified by cis-acting natural variation and a cornichon homolog.PLoS genetics · 2025Article
- Proline transporters balance the salicylic acid-mediated trade-off between regeneration and immunity in plants.bioRxiv : the preprint server for biology · 2025Article
- Plant metacaspases orchestrate wound-induced pathways for immunity and tissue regeneration.The Plant journal : for cell and molecular biology · 2025Article
- The pan genome analysis ofHorticulture research · 2025Article
- The mechanism of PGR-free direct organogenesis in Lycium ruthenicum leaf explants revealed by RNA-Seq and phytohormone metabolome co-analysis.BMC plant biology · 2025Article
- Water availability positions auxin response maxima to determine plant regeneration fates.Nature plants · 2025Article
- Regeneration and defense: unveiling the molecular interplay in plants.The New phytologist · 2025Review
- ChnagG Plays the Role of 5-Salicylate Hydroxylase in the Gentisic Acid Pathway of Salicylic Acid Metabolism in Cochliobolus heterostrophus.Molecular plant pathology · 2025Article
- Evaporative cooling signals for wound healing in plants.bioRxiv : the preprint server for biology · 2025Article
- Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration.Developmental cell · 2025Article
- De novo root regeneration from leaf explant: a mechanistic review of key factors behind cell fate transition.Planta · 2025Review
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9 authors at 2 institutions in 1 country.
Funding
Abstract
Wounding is a trigger for both regeneration and defense in plants, but it is not clear whether the two responses are linked by common activation or regulated as trade-offs. Although plant glutamate-receptor-like proteins (GLRs) are known to mediate defense responses, here, we implicate GLRs in regeneration through dynamic changes in chromatin and transcription in reprogramming cells near wound sites. We show that genetic and pharmacological inhibition of GLR activity increases regeneration efficiency in multiple organ repair systems in Arabidopsis and maize. We show that the GLRs work through salicylic acid (SA) signaling in their effects on regeneration, and mutants in the SA receptor NPR1 are hyper-regenerative and partially resistant to GLR perturbation. These findings reveal a conserved mechanism that regulates a trade-off between defense and regeneration, and they also offer a strategy to improve regeneration in agriculture and conservation.
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