ArticleBMC neurology2022
Recovery and long term functional outcome in people with critical illness polyneuropathy and myopathy: a scoping review.
Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Guideline on multimodal rehabilitation for patients with post-intensive care syndrome.Critical care (London, England) · 2023Guideline
- Heart rate variability biofeedback for critical illness polyneuropathy: a randomized sham-controlled study.European journal of neurology · 2024Trial
- Electrophysiology of Neuromuscular Disorders in Critical Illness.Muscle & nerve · 2026Review
- ICU-Acquired Weakness: Diagnostic Yield of a Clinical Diagnosis with Additional Quantification of Myosin Loss in Adult Critically Ill Patients.Journal of clinical medicine · 2026Article
- ICU-Acquired Weakness: An Unsolved Clinical Problem: A Narrative Review.Journal of clinical medicine · 2026Review
- Development and initial psychometric evaluation of a questionnaire for post intensive care recovery - PIR.Journal of patient-reported outcomes · 2026Article
- Factors Influencing Functional Recovery in People After Chronic Critical Illness During Early Neurological Rehabilitation.Journal of multidisciplinary healthcare · 2026Article
- Article
- Mitochondrial Dysfunction Contributes to Sustained Muscle Loss After Cardiac Surgery: A Prospective Observational Study.Journal of cachexia, sarcopenia and muscle · 2025Observational
- A novel short-course, low-intensity blood-flow-restricted exercise (BFRE) regimen to study satellite cell function in critical illness survivors with sustained muscle atrophy following intensive care unit-acquired weakness (ICUAW).Frontiers in physiology · 2025Article
- Beta-hydroxy-beta-methyl butyrate supplementation in critically ill patients: a systematic review and meta-analysis of randomized controlled trials.Frontiers in nutrition · 2025Article
- Comprehensive assessment and progression of health status during neurorehabilitation in survivors of critical illness: a prospective cohort study.Annals of intensive care · 2024Article
- Hydroxychloroquine Mitigates Cytokine Storm and Prevents Critical Illness Neuromyopathy in a Rat Sepsis Model.Medicina (Kaunas, Lithuania) · 2024Article
- Balance function in critical illness survivors and evaluation of psychometric properties of the Mini-BESTest.Scientific reports · 2024Article
- Article
- Safety and effectiveness of neuromuscular electrical stimulation in cardiac surgery: A systematic review.World journal of cardiology · 2024Article
- A scoping review of preclinical intensive care unit-acquired weakness models.Frontiers in physiology · 2024Article
- Quantitative muscle MRI displays clinically relevant myostructural abnormalities in long-term ICU-survivors: a case-control study.BMC medical imaging · 2023Article
- Case report: Personalized adapted motor activity in a COVID-19 patient complicated by critical illness polyneuropathy and myopathy.Frontiers in physiology · 2022Article
- Case Report: Functional Outcome of COVID-19 Subjects With Myasthenia Gravis and Critical Illness Polyneuropathy.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntensive care unit acquired weakness (ICUAW), embraces an array of disorders labeled "critical illness polyneuropathy" (CIP), "critical illness myopathy" (CIM) or "critical illness polyneuromyopathy" (CIPNM). Several studies have addressed the various characteristics of ICUAW, but the recovery is still unclear.
objectiveThe present review investigated the recovery and the long-term functional outcome of subjects with ICUAW, whether the types of ICUAW have different outcomes and whether there is any supporting evidence.
methodsLiterature search was performed from MEDLINE/PubMed, CINAHL, EMBASE, PeDro, Web of Science and Scopus. Inclusion criteria were: i) sample size including five or more subjects; ii) subjects who suffered from ICUAW and/or CIP, CIM and CIP/CIM; iii) ICUAW ascertained by EMG. Follow-ups longer than one year were defined as long-term.
resultsTwenty-nine studies met the inclusion criteria. In total, 788 subjects with ICUAW were enrolled: 159 (20.1%) died and 588 (74.6%) were followed. Of all the included patients, 613 (77.7%) had CIP, 82 (10.4%) CIM and 56 (7.1%) CIP/CIM. Overall, 70.3% of the subjects with ICUAW fully recovered. Seven (24.1%) studies had a follow-up longer than 1 year (range 2-8) with 173 (21.9%) subjects enrolled globally and 108 followed. Of these subjects, 88.8% gained full recovery. Most of the studies did not use proper functional scales and only 4 and 3 studies employed the Barthel scale and the Functional Independence Measure (FIM) scale. Differentiation between the types of ICUAW was performed in 7 studies, but only 3 studies reported that subjects with CIM had a better prognosis and earlier recovery than subjects with CIP/CIM.
conclusionsSubjects with ICUAW could achieve good recovery and could improve at follow-up. However, the quality of the published studies due to short follow-ups and the paucity of defined outcome measures require confirms.
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