Evidence map›Paper›PMID 35148420›Full record

Observational studyRevista de neurologia2022

[Prognosis of patients assisted in the emergency unit by the 'TIA protocol' in a third-level hospital at 90 days].

M Marín-Gracia, A López-Bravo, E Jiménez-Jara, D Cantero-Lozano, M P Navarro-Pérez, E Garcés-Antón, F Cueva-Recalde, M J Gimeno-Peribáñez, A García-Noain, C Tejero-Juste and 2 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Revista de neurologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

M Marín-GraciaHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
A López-BravoHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
E Jiménez-JaraHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
D Cantero-LozanoHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
M P Navarro-PérezHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
E Garcés-AntónHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
F Cueva-RecaldeHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
M J Gimeno-PeribáñezHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
A García-NoainHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
C Tejero-JusteHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
G Barón-EsquivasHospital Universitario Virgen del Rocío, Sevilla, España.
C Pérez-LázaroHospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, España.
Hospital Clínico Universitario Lozano Blesa · ESHospital Universitario Reina Sofía · ESHospital Universitario Virgen del Rocío · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCare models developed for the rapid management of patients with transient ischaemic attack (TIA) are safe, effective and reduce recurrence rates. The aim is to determine the prevalence of cardiovascular events at 90 days. PATIENTS AND

methodsAn observational, analytical, cross-sectional study was conducted. Adult male and female patients seen in the emergency department using the 'TIA protocol' between January 2016 and December 2019 were analysed. Data were collected on clinical variables, complementary tests, treatment and cardiovascular events (stroke/TIA, acute coronary syndrome or death due to cardiovascular causes) at 90 days. The study was approved by the Research Ethics Committee of Aragon.

resultsThe TIA protocol was performed on 163 out of 591 patients diagnosed with TIA in the emergency department. Brain CT and neurosonology scans were performed in 100% and a 24-hour Holter-electrocardiogram was carried out in 52.1%; atrial fibrillation (AF) was detected in 3.6% of them. An MRI brain scan was performed in 78.4% and acute ischaemic injury was seen in diffusion sequences (DWI+) in 13.5%. The prevalence of cardiovascular events at 90 days was 4.9% (8): stroke, 3.1% (five TIAs); acute coronary syndrome, 0.6% (one); and death from cardiovascular causes, 1.2% (two). Major adverse cardiovascular events were significantly associated with a history of ischaemic heart disease (p = 0.014). Cardiovascular death was associated with a history of AF (p = 0.008), anticoagulants at discharge (p = 0.007) and no antiplatelet therapy at discharge (p = 0.012), and there was a tendency towards an association with a history of type 2 diabetes mellitus (p = 0.05).

conclusionsRapid TIA protocols allow early care and avoid hospital admissions, without increasing the incidence of cardiovascular events or recurrence of stroke or TIA at 90 days.

Indexed as

AgedClinical ProtocolsCross-Sectional StudiesEmergency Service, HospitalFemaleHumansIschemic Attack, TransientMaleMiddle AgedPrevalencePrognosisRetrospective StudiesTertiary Care CentersTime Factors

Identifiers

PMID35148420
PMCPMC11502175
OpenAlexW4212898835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.