Evidence map›Paper›PMID 35148234›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2022

Trypsin cleavage of the β

Jing Zhu, Susan F Steinberg

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. BetaJACC. Basic to translational science · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jing ZhuDepartment of Pharmacology, Columbia University, New York City, New York.
Susan F SteinbergDepartment of Pharmacology, Columbia University, New York City, New York.ORCID 0000-0002-2927-8570
Columbia University · US

Funding

A novel molecular determinant of the cardiac beta1-adrenergic receptor responseR01HL138468 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STEINBERG, SUSAN F · 2018 to 2021
$2.4M
NHLBI NIH HHS R01 HL138468
6 · The paper itself

Abstract

β

Indexed as

Myocytes, CardiacReceptors, Adrenergic, beta-1CatecholaminesProteolysisSignal TransductionTrypsinCatecholaminesReceptors, Adrenergic, beta-1Trypsincardiomyocytestrypsinβ1-adrenergic receptors

Identifiers

PMID35148234
PMCPMC8897006
OpenAlexW4211137150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.