Evidence map›Paper›PMID 35147789›Full record

ArticleClinical oral investigations2022

The association between molar incisor hypomineralization and oral health-related quality of life: a cross-sectional study.

K Elhennawy, O Rajjoub, D R Reissmann, M-S Doueiri, R Hamad, I Sierwald, V Wiedemann, K Bekes, P-G Jost-Brinkmann

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Non- and minimally invasive management of hypersensitivity in molar-incisor hypomineralisation (MIH) at home and in clinical practice: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
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  5. Comparative study of articaine 4% versus lidocaine 2% in the local anesthesia of permanent mandibular first molars affected by MIH: a randomized controlled trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023
    Trial
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  8. Molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM): do we need to alter terminology and definition? A scoping review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Review
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  10. Children with unilateral molar-incisor hypomineralisation (MIH) may exhibit contralateral temporalis and masseter muscle hyperactivity: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Observational
  11. Hypersensitivity associated with molar-incisor hypomineralisation (MIH) among elementary schoolchildren in Bavaria, Germany: results from a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  12. Causal effect of molar incisor hypomineralisation on oral health-related quality of life of Australian children aged 7-16 years.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

K ElhennawyDepartment of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, Berlin, Germany. Karim.elhennawy@charite.de.ORCID http://orcid.org/0000-0002-5216-9452
O RajjoubDepartment of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, Berlin, Germany.
D R ReissmannDepartment of Prosthetic Dentistry, Center for Dental and Oral Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
M-S DoueiriDepartment of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, Berlin, Germany.
R HamadDepartment of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, Berlin, Germany.
I SierwaldDepartment of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, Berlin, Germany.
V WiedemannPrivate practice "MUNDWERK", Berlin, Germany.
K BekesDepartment of Paediatric Dentistry, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria.
P-G Jost-BrinkmannDepartment of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charite - Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Humboldt-Universität zu Berlin · DEMedical University of Vienna · ATUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to assess the association between molar incisor hypomineralization (MIH) and the oral health-related quality of life (OHRQoL) in a group of 7- to 14-year-old children in Berlin, Germany. MATERIALS AND

methodsThe cross-sectional study consisted of a consecutive sample of 317 children, aged 7-14 years (49% girls, 51% boys; mean age, 8.71). Data were collected between June 2018 and December 2019. MIH was diagnosed using the criteria of the European Academy of Paediatric Dentistry. OHRQoL was assessed using the German 19-item version of the Child Oral Health Impact Profile (COHIP-G19). Differences in COHIP-19 summary scores between controls without MIH and MIH patients and with regards to MIH severity were tested for statistical significance using t test and analysis of variance (ANOVA), respectively.

resultsData were obtained for 217 untreated MIH patients and 100 controls. OHRQoL of MIH patients was significantly more impaired than of controls indicated by COHIP-19 mean scores (60.9 ± 10.7 vs. 67.9 ± 7.8; p < 0.001). Patients with severe MIH (59.6 ± 11.0) reported significantly worse OHRQoL than patients with mild MIH (63.6 ± 9.1; p = 0.013).

conclusionsMIH has a significant negative impact on the children's OHRQoL. Patients with severe MIH experience a greater negative impact on OHRQoL than those diagnosed with mild MIH. CLINICAL SIGNIFICANCE: MIH is one of the major dental problems of our time; pediatric dentists should be aware of its impact on the OHRQoL of the patient.

Indexed as

Dental Enamel HypoplasiaQuality of LifeAdolescentChildCross-Sectional StudiesFemaleHumansMalePrevalenceSurveys and QuestionnairesCOHIPDental managementHypersensitivityMIHMolar incisor hypomineralizationOral health-related quality of lifeQuality of life

Identifiers

PMID35147789
PMCPMC9072460
OpenAlexW4211236755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.