Evidence map›Paper›PMID 35147501›Full record

ArticleJMIR formative research2022

Medication Optimization Among People With Type 2 Diabetes Participating in a Continuous Glucose Monitoring-Driven Virtual Care Program: Prospective Study.

Amit R Majithia, David M Erani, Coco M Kusiak, Jennifer E Layne, Amy Armento Lee, Francis R Colangelo, Robert J Romanelli, Scott Robertson, Shayla M Brown, Ronald F Dixon and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03865381 (Onduo Virtual Diabetes Clinic Study), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03865381 nacompletednot on this map

Onduo Virtual Diabetes Clinic Study

TypeinterventionalSponsorVerily Life Sciences LLCRan2019 to 2020Enrolled60ConditionsDiabetes Mellitus, Type 2ArmsOnduo App
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Amit R MajithiaDepartment of Medicine, University of California San Diego School of Medicine, La Jolla, CA, United States.ORCID https://orcid.org/0000-0001-9978-2644
David M EraniOnduo Professionals PC, Newton, MA, United States.ORCID https://orcid.org/0000-0003-1012-6312
Coco M KusiakVerily Life Sciences, South San Francisco, CA, United States.ORCID https://orcid.org/0000-0002-5888-9303
Jennifer E LayneOnduo LLC, Newton, MA, United States.ORCID https://orcid.org/0000-0001-7144-7051
Amy Armento LeeVerily Life Sciences, South San Francisco, CA, United States.ORCID https://orcid.org/0000-0002-7564-7891
Francis R ColangeloAllegheny Health Network, Monroeville, PA, United States.ORCID https://orcid.org/0000-0003-4616-0133
Robert J RomanelliSutter Health, Palo Alto, CA, United States.ORCID https://orcid.org/0000-0001-6686-9962
Scott RobertsonVerily Life Sciences, South San Francisco, CA, United States.ORCID https://orcid.org/0000-0003-0378-1052
Shayla M BrownOnduo LLC, Newton, MA, United States.ORCID https://orcid.org/0000-0001-8880-2953
Ronald F DixonOnduo LLC, Newton, MA, United States.ORCID https://orcid.org/0000-0003-1933-0387
Howard ZisserVerily Life Sciences, South San Francisco, CA, United States.ORCID https://orcid.org/0000-0002-8927-9671
Allegheny Health Network · USSutter Health · USUniversity of California San Diego · USWilliam James College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Onduo virtual care program for people with type 2 diabetes (T2D) includes a mobile app, remote lifestyle coaching, connected devices, and telemedicine consultations with endocrinologists for medication management and prescription of real-time continuous glucose monitoring (RT-CGM) devices. In a previously described 4-month prospective study of this program, adults with T2D and baseline glycated hemoglobin (HbA

objectiveThe objective of this analysis was to evaluate medication optimization and management in the 4-month prospective T2D study.

methodsStudy participants received at least 1 telemedicine consultation with an Onduo endocrinologist for diabetes medication management and used RT-CGM intermittently to guide therapy and dosing. Medication changes were analyzed.

resultsOf 55 participants, 48 (87%) had a medication change consisting of a dose change, addition, or discontinuation. Of these, 15 (31%) participants had a net increase in number of diabetes medication classes from baseline. Mean time to first medication change for these participants was 36 days. The percentage of participants taking a glucagon-like peptide-1 receptor agonist increased from 25% (12/48) to 56% (n=27), while the percentages of participants taking a sulfonylurea or dipeptidyl peptidase 4 inhibitor decreased from 56% (n=27) to 33% (n=16) and 17% (n=8) to 6% (n=3), respectively. Prescriptions of other antidiabetic medication classes including insulin did not change significantly.

conclusionsThe Onduo virtual care program can play an important role in providing timely access to guideline-based diabetes management medications and technologies for people with T2D.

trial registrationClinicalTrials.gov NCT03865381; https://clinicaltrials.gov/ct2/show/NCT03865381.

Indexed as

appcoachingcontinuous glucose monitoringdiabetesdigital healthGLP-1 receptor agonistHbA1clifestylemedicationmonitoringoptimizationprospectiveself-managementtelemedicinetype 2 diabetesvirtual care

Identifiers

PMID35147501
PMCPMC9019640
OpenAlexW4210783935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.