ReviewImmunity, inflammation and disease2022
Neurological disorders in HIV: Hope despite challenges.
Review in Immunity, inflammation and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Epidemiology and etiology of brain cancer in Africa: A systematic review.Brain and behavior · 2023Pooled it
- Multiplanar MRI approach to the differential diagnosis of central nervous system tumors and tumor-like lesions in patients with HIV: what radiologists need to know.Frontiers in medicine · 2026Review
- Oxidative Stress in HIV-Associated Neurodegeneration: Mechanisms of Pathogenesis and Therapeutic Targets.International journal of molecular sciences · 2025Review
- Ataxia in Africa: current efforts and recommendations.Annals of medicine and surgery (2012) · 2025Review
- The miRNomics of antiretroviral therapy-induced obesity.Functional & integrative genomics · 2025Review
- Addressing Cardiometabolic Challenges in HIV: Insights, Impact, and Best Practices for Optimal Management-A Narrative Review.Health science reports · 2025Article
- The Role of Electrochemical Sensors in Enhancing HIV Detection.Current HIV research · 2025Review
- Sera from people with HIV and depression induce commensurate metabolic alterations in astrocytes: toward precision diagnoses and therapies.NeuroImmune pharmacology and therapeutics · 2024Article
- HIV-1 Structural Proteins or Cell-Signaling Factors? That Is the Question!Current issues in molecular biology · 2024Review
- Rising meningitis in USA and Mexico: insights from the fatal outbreak.Annals of medicine and surgery (2012) · 2024Review
- Prediction of incidence of neurological disorders in HIV-infected persons in Taiwan: a nested case-control study.BMC infectious diseases · 2023Article
- Long-term cognitive dysfunction after the COVID-19 pandemic: a narrative review.Annals of medicine and surgery (2012) · 2023Article
- Selection of cognitive impairment screening tools for longitudinal implementation in an HIV clinical care setting.AIDS care · 2023Review
- Poliovirus returns to the UK after nearly 40 years: current efforts and future recommendations.Postgraduate medical journal · 2022Article
- Hepatitis A virus outbreak in Lebanon: Is it a matter of concern?Annals of medicine and surgery (2012) · 2022Article
- Yellow fever outbreak in Kenya: A review.Annals of medicine and surgery (2012) · 2022Review
- A short communication of Nipah virus outbreak in India: An urgent rising concern.Annals of medicine and surgery (2012) · 2022Article
- Measles outbreak in Zimbabwe: An urgent rising concern.Annals of medicine and surgery (2012) · 2022Article
- Polio returns to the USA: An epidemiological alert.Annals of medicine and surgery (2012) · 2022Article
- A review on acute, severe hepatitis of unknown origin in children: A call for concern.Annals of medicine and surgery (2012) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHuman Immunodeficiency virus (HIV) is a virus that causes several diseases by attacking the human immune system. It is transmitted by contact with certain bodily fluids of an infected person, most commonly during unprotected sex, through sharing needles, or from mother to baby during pregnancy, birth or breastfeeding. The central nervous system is not spared from this virus, as HIV has been shown to induce several neurological disorders. However most neurological pathologies (such as dementia, infections, meningitis, and neuropathy) rarely show until late stages, in this case, after the patients develop acquired immunodeficiency syndrome (AIDS). This article aims to review the neurological disorders in the HIV population and the attempts initiated to limit the disease. METHODOLOGY: Data were collected from medical journals published on PubMed, Ovid MEDLINE, Science Direct and Embase bibliographical databases with a predefined search strategy. All articles considering neurological disorders associated with HIV were considered.
resultsTo date, the pathogenesis of HIV-associated neurological complications remains poorly elucidated; thus, imposing a hindrance and limitations on the treatment options. Nevertheless, some studies have reported alterations in dendritic spine as the causative agent for developing brain damage.
conclusionHIV remains one of the most serious global health challenges, with neurological manifestations imposing a major concern among patients with HIV. Despite the availability and efficacy of antiretroviral therapies, yet, the risk of developing neurological complications remains relatively high among patients with HIV. Thus, the 2030 HIV vision must focus on further preventive measures to protect HIV patients from developing such neurological complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.