ArticleESC heart failure2022
Blood urea nitrogen to serum albumin ratio as a new prognostic indicator in critical patients with chronic heart failure.
Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of albumin-based indices for mortality after heart failure: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Prognostic significance of the blood urea nitrogen-to-serum albumin ratio in patients with septic shock.Experimental and therapeutic medicine · 2026Article
- Associations of the C-Reactive Protein-Albumin-Lymphocyte Index, Red Cell Distribution Width-Albumin Ratio, and Blood Urea Nitrogen-Albumin Ratio With All-Cause and Cardiovascular Mortality Among Adults With Preclinical Heart Failure.Clinical cardiology · 2026Article
- Association between blood urea nitrogen to albumin ratio and 28-day mortality of acute heart failure in intensive care unit: analysis based on MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- Article
- Association between blood urea nitrogen-to-albumin ratio and postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass grafting: a retrospective observational study.BMC cardiovascular disorders · 2026Observational
- Association between blood urea nitrogen-to-albumin ratio and mortality among atrial fibrillation patients admitted to the intensive care unit.BMC cardiovascular disorders · 2026Article
- The association between blood urea nitrogen to serum albumin ratio and all-cause mortality in critically ill patients with atrial fibrillation.European journal of medical research · 2026Article
- Albumin, urea-to-albumin ratio, or the albumin-to-creatinine ratio to predict outcomes in heart failure with mildly reduced ejection fraction.European journal of clinical investigation · 2026Observational
- Blood urea nitrogen-to-serum albumin ratio as a predictor of long-term mortality in patients with acute heart failure.Frontiers in cardiovascular medicine · 2026Article
- Blood Urea Nitrogen to Albumin Ratio is Associated with Diabetic Peripheral Neuropathy in Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- BUN-albumin ratio as a prognostic marker in decompensated heart failure with reduced ejection fraction.American heart journal plus : cardiology research and practice · 2026Article
- Blood urea nitrogen to albumin ratio as a robust predictor of in-hospital mortality in patients with predicted severe acute pancreatitis: a retrospective multicenter observational study.International journal of surgery (London, England) · 2026Observational
- Bridging the gap between biomarkers and bedside decisions: the prognostic value of the blood urea nitrogen-to-albumin ratio in sepsis-associated AKI.Frontiers in nutrition · 2026Article
- The association between blood urea nitrogen to albumin ratio and 28-day ICU mortality in sepsis patients: a retrospective cohort study.European journal of medical research · 2025Article
- Association between blood urea nitrogen-to-albumin ratio and mortality in ICU patients with chronic obstructive pulmonary disease: data from the MIMIC IV database.BMC geriatrics · 2025Article
- Coagulation biomarkers as prognostic indicators in heart failure: A systematic review and meta-analysis of 14,773 patients.Global cardiology science & practice · 2025Article
- Independent prognostic importance of blood urea nitrogen to albumin ratio in critically ill patients with congestive heart failure.Scientific reports · 2025Article
- BUN-to-ALB ratio as an effective predictor of 30 day mortality in ADHF patients in eastern China.ESC heart failure · 2025Article
- The ABIC score for assessing long-term outcomes in elderly hospitalized patients with acute exacerbations of chronic heart failure.BMC cardiovascular disorders · 2025Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsChronic heart failure (CHF) is often a common comorbidity in critically ill patients admitted to the intensive care unit (ICU) and carries an extremely poor prognosis. The study aimed to investigate the relationship between the blood urea nitrogen to serum albumin ratio (BAR) and the prognosis of patients with CHF admitted to the ICU. METHODS AND
resultsThis retrospective cohort study included 1545 critically ill patients with CHF as a diagnosed comorbidity admitted to the ICU deposited in the MIMIC-III database, of whom 90 day all-cause mortality was 27.6% (n = 427) and in-hospital mortality was 17.3% (n = 267). The results of multiple logistic regression analysis indicated that BAR is an independent risk factor for in-hospital mortality in critically ill patients with CHF [compared with BAR ≤ 0.83; 0.83 < BAR ≤ 1.24: odds ratio (OR) 2.647, 95% confidence interval (CI) 1.797-3.900, P < 0.001; BAR ≥ 1.24: OR 3.628, 95% CI 2.604-5.057, P < 0.001]. Multiple COX regression analysis found a relationship between BAR and all-cause mortality at 90 day follow-up (0.83 < BAR ≤ 1.24: OR 1.948, 95% CI 1.259-3.014, P < 0.003; BAR ≥ 1.24: OR 1.807, 95% CI 1.154-2.830, P < 0.01; BAR ≤ 0.83 as a reference). Kaplan-Meier curves also showed similar results as well (P < 0.001). The areas under the receiver operating characteristic curves for predicting in-hospital mortality and 90 day all-cause mortality were 0.622 and 0.647, respectively.
conclusionsBAR is an independent risk factor for in-hospital mortality and 90 day mortality in critically ill patients with CHF admitted to the ICU.
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