ArticleThe clinical respiratory journal2022
The alterations of retinal vasculature detected on optical coherence tomography angiography associated with chronic obstructive pulmonary disease.
Article in The clinical respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Diagnostic value of ocular imaging biomarkers in chronic obstructive pulmonary disease: a multicenter prospective cross-sectional study.Journal of thoracic disease · 2026Article
- Analysis of factors influencing retinal thickness in chronic obstructive pulmonary disease and hypertension: a cross-sectional study in a community-dwelling middle-aged and elderly population.Frontiers in medicine · 2026Article
- The COPD-driven "lung-eye axis": mechanisms and clinical evidence of ocular disease.Frontiers in medicine · 2026Review
- Cross-Trait Genome-Wide Association Study Identifies Shared Genetic Architecture Between COPD and Retinal Vascular Phenotypes.International journal of chronic obstructive pulmonary disease · 2026Article
- Relationship between intraocular pressure and pulmonary function.Scientific reports · 2025Article
- Evaluation of Retinal and Posterior Segment Vascular Changes Due to Systemic Hypoxia Using Optical Coherence Tomography Angiography.Journal of clinical medicine · 2024Article
- The alterations of retinal vasculature detected on optical coherence tomography angiography associated with chronic obstructive pulmonary disease.The clinical respiratory journal · 2022Article
- Optical coherence tomography angiography as a surrogate marker for end-organ resuscitation in sepsis: A review.Frontiers in medicine · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to evaluate the retinal vasculature of the macula and optic disc in patients with chronic obstructive pulmonary disease (COPD) by optical coherence tomography angiography (OCTA).
methodsThe right eyes of 70 COPD patients and 71 healthy individuals were evaluated. These patients had moderate airflow limitation and mean PO
resultsThe COPD group had a significant decrease in the vascular density in the superficial (fovea [p = 0.019]; parafovea [p = 0.013]; and perifovea [p = 0.001]) and deep capillary plexus (fovea [p = 0.028]; parafovea [p = 0.005]; and perifovea [p = 0.002]). Also, the enlargement of the FAZ (p = 0.002) and a decrease in the peripapillary vascular density (p = 0.006) were observed in the COPD group. There was a positive correlation between PO
conclusionHypercapnia, respiratory acidosis, and chronic hypoxia associated with COPD may affect the macula and optic nerve, resulting in a serious decrease in vascular density, and OCTA can be a very important tool in the follow-up and treatment of these patients.
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Registered trials
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