Evidence map›Paper›PMID 35146745›Full record

ArticleThe Journal of small animal practice2022

Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs.

V Argent, R Perillo, N Jeffery, P Freeman

Abstract read
In one paragraph

Article in The Journal of small animal practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Surgical management of Cd1-Cd2 intervertebral disc extrusion in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

V ArgentDepartment of Small Animal Neurology, Davies Veterinary Specialists, Higham Gobion, SG5 3HR, UK.ORCID 0000-0002-8830-9605
R PerilloDepartment of Small Animal Neurology, Clinica Veterinaria San Marco, Viale dell'Industria, Veggiano, 35030, Italy.
N JefferyDepartment of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, 77843, USA.
P FreemanDepartment of Small Animal Neurology, Queen's Veterinary School Hospital, Cambridge, CB3 0ES, UK.ORCID 0000-0001-6326-5573

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesReport the rate of recurrent clinical signs following successful treatment of cervical intervertebral disc extrusion, and explore the association between treatment method and recurrence. MATERIALS AND

methodsMedical records of dogs with MRI- or CT-confirmed cervical intervertebral disc extrusion were reviewed to verify that they recovered. Type of treatment, site of initial extrusion and whether dogs re-presented with recurrent clinical signs were recorded. Recurrence was considered presumed if based on clinical signs or confirmed if based on repeat cross-sectional imaging.

resultsComplete recovery was documented following medical (36/119, 30.3%) or surgical (83/119, 69.7%) management of initial cervical disc extrusion. There was a recurrence of consistent clinical signs in 40 of 119 (34%) cases, of which 27 of 83 (33%) were initially managed surgically and 13 of 36 (36%) medically. In 24 of 40 (60%) cases, there was imaging confirmation of recurrent extrusion; in medically managed dogs, recurrence mostly occurred at the same site, whereas after surgery, recurrence most commonly involved an adjacent disc. Of the 40 recurrences, 32 (80%) occurred within 2 years of diagnosis. Rate of recurrence was similar between treatment methods in both univariable and multivariable time-to-event analyses (hazard ratio 1.03; 95% confidence interval: 0.67 to 1.53; P=0.87). CLINICAL SIGNIFICANCE: Following successful initial medical or surgical treatment, clinical signs consistent with recurrent cervical disc extrusion occurred with similar frequency. Medically treated cases tended to have recurrence at the same site as initial presentation, whereas surgical treatment prevented this. Recurrence usually occurred within 2 years. The retrospective study design, small number of recurrences and lack of imaging confirmation of every recurrence should be considered when interpreting the results.

Indexed as

Dog DiseasesIntervertebral DiscIntervertebral Disc DisplacementAnimalsDogsMagnetic Resonance ImagingRecurrenceRetrospective Studies

Identifiers

PMID35146745
PMCPMC9303190

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.