Evidence map›Paper›PMID 35146618›Full record

ArticleAdvances in experimental medicine and biology2022

Proof of Concept for the Use of Immersive Virtual Reality in Upper Limb Rehabilitation of Multiple Sclerosis Patients.

Rachel-Anne Hollywood, Matthieu Poyade, Lorna Paul, Amy Webster

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07193602 (Home-based Virtual Reality), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07193602 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Home-based Virtual Reality (VR) Headset-based Dexterity Training in Multiple Sclerosis: a Randomized-controlled Trial

TypeinterventionalSponsorChristian KammRan2026 to 2028Enrolled60ConditionsMultiple SclerosisArmsVR-based dexterity training in MS, mediation program
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rachel-Anne HollywoodThe Glasgow School of Art, Glasgow, Scotland, UK.
Matthieu PoyadeThe Glasgow School of Art, Glasgow, Scotland, UK.
Lorna PaulGlasgow Caledonian University, Glasgow, Scotland, UK.
Amy WebsterGlasgow Caledonian University, Glasgow, Scotland, UK.
Glasgow Caledonian University · GBGlasgow School of Art · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is a debilitating disease which gradually reduces motor function and mobility. Virtual reality (VR) has been successfully utilised in support of existing therapeutic approaches for many different conditions, and new innovative and experimental features could be the future of VR rehabilitation. The Quest is a new headset by Oculus, with its built-in tracking, relatively low cost, portability and lack of reliance on expensive processing heavy PCs to power it, and could be an ideal system to facilitate at-home or clinic-based upper limb rehabilitation. A hand-tracking-based rehabilitation game aimed at people with MS was developed for Oculus Quest using Unity. Two distinct games were made to replicate different types of hand exercises, piano playing for isolated finger flexion and maze tracking for coordination and arm flexion. This pilot study assesses the value of such approach along with evaluating intrinsic and extrinsic methods of providing feedback, namely, positive scoring, negative scoring and audio response. One physiotherapist and two individuals with MS were surveyed. Participant response was positive although small sample size impacts the user testing validity of the results. Future research is recommended to build off the data gathered as a pilot study and increase sample size to collect richer feedback.

Indexed as

Multiple SclerosisNeurological RehabilitationVirtual RealityHumansPilot ProjectsUpper ExtremityHand-trackingIntrinsic and extrinsic feedbackMultiple sclerosisOculus QuestUpper limb rehabilitationVirtual reality rehabilitation

Identifiers

PMID35146618
OpenAlexW4211158285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.