ArticlePediatrics2022
Ten-Year Survival of Children With Congenital Anomalies: A European Cohort Study.
Article in Pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 2 citations in OpenAlex.
- Survival, hospitalisation and surgery in children born with Pierre Robin sequence: a European population-based cohort study.Archives of disease in childhood · 2023Pooled it
- Association between birth location and short-term outcomes for babies with gastroschisis, congenital diaphragmatic hernia and oesophageal fistula: a systematic review.BMJ paediatrics open · 2023Pooled it
- Survival of children with rare structural congenital anomalies: a multi-registry cohort study.Orphanet journal of rare diseases · 2022Pooled it
- Associations of major congenital anomalies, long-term health conditions, and socioeconomic deprivation with educational attainment in Wales: A population-based data linkage study.PLoS medicine · 2026Article
- Burden of digestive congenital anomalies in the Middle East and North Africa region between 1990 and 2021.Journal of health, population, and nutrition · 2026Article
- Prenatal detection and outcome of major heart defects in a country with universal screening.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Article
- Analysis of Prevalence and Mortality Among Neonates and Children With Intestinal Atresia: A Multinational Study, 1974-2015.Birth defects research · 2026Article
- Genetic Diagnoses Among Congenital Anomaly Cases in Europe: Data From the EUROCAT Network.Paediatric and perinatal epidemiology · 2026Article
- Mortality amongst European children with congenital anomalies: Associations with socio-economic status in the EUROLINKCAT cohort.PloS one · 2026Observational
- Mortality among individuals with congenital malformations who reach adulthood: long-term follow-up of the Jerusalem Perinatal Study cohort.International journal of epidemiology · 2025Article
- Risk factors for hospital admission and length of stay for children with and without congenital anomalies: a EUROlinkCAT cohort study.BMJ paediatrics open · 2025Article
- The Healthcare Needs of Children With Down Syndrome in the First Year of Life: An Analysis of the EUROlinkCAT Data Linkage Study.Paediatric and perinatal epidemiology · 2025Article
- Health outcomes and drug utilisation in children with Noonan syndrome: a European cohort study.Orphanet journal of rare diseases · 2025Article
- School-recorded special educational needs provision in children with major congenital anomalies: A linked administrative records study of births in England, 2003-2013.International journal of population data science · 2025Article
- Article
- Classification of isolated versus multiple birth defects: An automated process for population-based registries.American journal of medical genetics. Part A · 2024Article
- The Association of Prenatal Diagnoses with Mortality and Long-Term Morbidity in Children with Specific Isolated Congenital Anomalies: A European Register-Based Cohort Study.Maternal and child health journal · 2024Article
- Timing of Cardiac Surgical Interventions and Postoperative Mortality in Children With Severe Congenital Heart Defects Across Europe: Data From the EUROlinkCAT Study.Journal of the American Heart Association · 2023Article
- Educational achievement of children with selected major congenital anomalies and associated factors: a Finnish registry-based study.European journal of public health · 2023Article
- Survival of neonates, infants, and children with birth defects: a population-based study in Texas, 1999-2018.Lancet regional health. Americas · 2023Article
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Authors and funding
25 authors at 17 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the survival up to age 10 for children born alive with a major congenital anomaly (CA).
methodsThis population-based linked cohort study (EUROlinkCAT) linked data on live births from 2005 to 2014 from 13 European CA registries with mortality data. Pooled Kaplan-Meier survival estimates up to age 10 were calculated for these children (77 054 children with isolated structural anomalies and 4011 children with Down syndrome).
resultsThe highest mortality of children with isolated structural CAs was within infancy, with survival of 97.3% (95% confidence interval [CI]: 96.6%-98.1%) and 96.9% (95% CI: 96.0%-97.7%) at age 1 and 10, respectively. The 10-year survival exceeded 90% for the majority of specific CAs (27 of 32), with considerable variations between CAs of different severity. Survival of children with a specific isolated anomaly was higher than in all children with the same anomaly when those with associated anomalies were included. For children with Down syndrome, the 10-year survival was significantly higher for those without associated cardiac or digestive system anomalies (97.6%; 95% CI: 96.5%-98.7%) compared with children with Down syndrome associated with a cardiac anomaly (92.3%; 95% CI: 89.4%-95.3%), digestive system anomaly (92.8%; 95% CI: 87.7%-98.2%), or both (88.6%; 95% CI: 83.2%-94.3%).
conclusionsTen-year survival of children born with congenital anomalies in Western Europe from 2005 to 2014 was relatively high. Reliable information on long-term survival of children born with specific CAs is of major importance for parents of these children and for the health care professionals involved in their care.
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