ArticleThe Journal of cell biology1986
The structure of cytoplasm in directly frozen cultured cells. II. Cytoplasmic domains associated with organelle movements.
Article in The Journal of cell biology, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 47 citations in OpenAlex.
- Growth cone macropinocytosis of neurotrophin receptor and neuritogenesis are regulated by neuron navigator 1.Molecular biology of the cell · 2022Article
- Neurite outgrowth is driven by actin polymerization even in the presence of actin polymerization inhibitors.Molecular biology of the cell · 2016Article
- Myosin II activity facilitates microtubule bundling in the neuronal growth cone neck.Developmental cell · 2008Article
- Organelle-cytoskeletal interactions: actin mutations inhibit meiosis-dependent mitochondrial rearrangement in the budding yeast Saccharomyces cerevisiae.Molecular biology of the cell · 1995Article
- Cytoskeletal remodeling during growth cone-target interactions.The Journal of cell biology · 1993Article
- Purified kinesin promotes vesicle motility and induces active sliding between microtubules in vitro.Proceedings of the National Academy of Sciences of the United States of America · 1991Article
- The ultrastructure of patch-clamped membranes: a study using high voltage electron microscopy.The Journal of cell biology · 1991Article
- Studies on the interaction between mitochondria and the cytoskeleton.Journal of bioenergetics and biomembranes · 1989Article
- The organization of myosin and actin in rapid frozen nerve growth cones.The Journal of cell biology · 1989Article
- Morphology of astroglial cells is controlled by beta-adrenergic receptors.The Journal of cell biology · 1987Article
- Five-parameter fluorescence imaging: wound healing of living Swiss 3T3 cells.The Journal of cell biology · 1987Article
- Dynamic shape changes of cytoplasmic organelles translocating along microtubules.The Journal of cell biology · 1987Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between organelle movement and cytoplasmic structure in cultured fibroblasts or epithelial cells was studied using video-enhanced differential interference contrast microscopy and electron microscopy of directly frozen whole mounts. Two functional cytoplasmic domains are characterized by these techniques. A central domain rich in microtubules is associated with directed as well as Brownian movements of organelles, while a surrounding domain rich in f-actin supports directed but often intermittent organelle movements more distally along small but distinct individual microtubule tracks. Differences in the organization of the cytoplasm near microtubules may explain why organelle movements are typically continuous in central regions but usually intermittent along the small tracks through the periphery. The central type of cytoplasm has a looser cytoskeletal meshwork than the peripheral cytoplasm which might, therefore, interfere less frequently with organelles moving along microtubules there.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.