Evidence map›Paper›PMID 35146346›Full record

ArticleLe infezioni in medicina2021

CURB-65 plus hypoalbuminemia: a new score system for prediction of the in-hospital mortality risk in patients with SARS-CoV-2 pneumonia.

Alessandra Oliva, Cristian Borrazzo, Maria Teresa Mascellino, Ambrogio Curtolo, Dania Al Ismail, Francesca Cancelli, Gioacchino Galardo, Tommaso Bucci, Giancarlo Ceccarelli, Gabriella d'Ettorre and 3 more

Abstract read
In one paragraph

Article in Le infezioni in medicina, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alessandra OlivaDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Cristian BorrazzoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Maria Teresa MascellinoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Ambrogio CurtoloDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Dania Al IsmailDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Francesca CancelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Gioacchino GalardoMedical Emergency Unit, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Tommaso BucciDepartment of General Surgery, Surgical Specialties and Organ Transplantation "Paride Stefanini", Sapienza University of Rome, Rome, Italy.
Giancarlo CeccarelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Gabriella d'EttorreDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Francesco PuglieseAnesthesiology and Intensive Care group, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Claudio M MastroianniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.
Mario VendittiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is the need of a simple but highly reliable score system for stratifying the risk of mortality and Intensive Care Unit (ICU) transfer in patients with SARS-CoV-2 pneumonia at the Emergency Room. PURPOSE: In this study, the ability of CURB-65, extended CURB-65, PSI and CALL scores and C-Reactive Protein (CRP) to predict intra-hospital mortality and ICU admission in patients with SARS-CoV-2 pneumonia were evaluated.

methodsDuring March-May 2020, a retrospective, single-center study including all consecutive adult patients with diagnosis of SARS-CoV-2 pneumonia was conducted. Clinical, laboratory and radiological data as well as CURB-65, expanded CURB-65, PSI and CALL scores were calculated based on data recorded at hospital admission.

resultsOverall, 224 patients with documented SARS-CoV-2 pneumonia were included in the study. As for intrahospital mortality (24/224, 11%), PSI performed better than all the other tested scores, which showed lower AUC values (AUC=0.890 for PSI

conclusionThe addition of albumin level to the easy-to-calculate CURB-65 score at hospital admission is able to improve the quality of prediction of intra-hospital mortality in patients with SARS-CoV-2 pneumonia.

Indexed as

CALL scoreCRPCURB-65extended CURB-65hypoalbuminemiaICU admissionmortalityPSI score

Identifiers

PMID35146346
PMCPMC8805501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.