Evidence map›Paper›PMID 35146209›Full record

ArticleAmerican journal of ophthalmology case reports2022

Secondary vitreoretinal lymphoma with spontaneous regression.

Wijak Kongwattananon, Aman Kumar, Jillian Simard, Henry E Wiley, H Nida Sen, Shilpa Kodati

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Wijak KongwattananonNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Aman KumarNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Jillian SimardNational Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Henry E WileyNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
H Nida SenNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Shilpa KodatiNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
National Eye Institute · USNational Cancer Institute · USNational Institutes of Health · USThai Red Cross Society · TH

Funding

Uveitis and Ocular Immunology FellowshipZIEEY000482 · NEI · NATIONAL EYE INSTITUTE · PI KODATI, SHILPA · 2009 to 2022
$4.6M
6 · The paper itself

Abstract

purposeTo report a patient with vitreoretinal lymphoma (VRL) secondary to systemic diffuse large B-cell lymphoma, who had two episodes of spontaneous regression. OBSERVATIONS: An 80-year-old Nicaraguan male with a history of treated systemic diffuse large B-cell lymphoma presented with decreased vision in his right eye over one year. The patient was found to have subretinal lesions and moderate vitreous opacities in his right eye. Cytological analysis of vitreous confirmed B-cell lymphoma. Following his systemic work-up, spontaneous clinical improvement was noted. There were no vitreoretinal or systemic lymphoma recurrences during one year of follow-up until the patient had new onset decreased vision in the left eye. He was presumed to have a recurrence of VRL supported by optical coherence tomography findings. Repeat systemic workup was negative for reoccurrence and the ocular lesions resolved spontaneously over 4 weeks.

conclusionsSpontaneous regression of intraocular lymphoma can rarely occur. Multimodal imaging has an essential role in diagnosing and monitoring recurrence of this disease.

Indexed as

Large B-cell lymphomaMultimodal imagingRecurrenceSpontaneous regressionVitreoretinal lymphoma

Identifiers

PMID35146209
PMCPMC8818703
OpenAlexW4210789075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.