Evidence map›Paper›PMID 35146118›Full record

ReviewInternational journal of cardiology. Heart & vasculature2022

Impact of new-onset versus pre-existing atrial fibrillation on outcomes after transcatheter aortic valve replacement/implantation.

Nso Nso, Kelechi Emmanuel, Mahmoud Nassar, Rubal Bhangal, Sostanie Enoru, Adedapo Iluyomade, Jonathan D Marmur, Onyedika J Ilonze, Senthil Thambidorai, Hakeem Ayinde

Open access · goldAbstract readReview
In one paragraph

Review in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Pre-Existing and New-Onset Atrial Fibrillation in Patients Undergoing Transcatheter Aortic Valve Implantation.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  4. Article
  5. Review
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  14. Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Nso NsoDepartment of Medicine, Icahn School of Medicine at Mount Sinai/NYC H+H/Queens, NY, USA.
Kelechi EmmanuelDepartment of Medicine, University of Pittsburgh Medical Center Pinnacle, PA, USA.
Mahmoud NassarDepartment of Medicine, Icahn School of Medicine at Mount Sinai/NYC H+H/Queens, NY, USA.
Rubal BhangalDepartment of Medicine, Icahn School of Medicine at Mount Sinai/NYC H+H/Queens, NY, USA.
Sostanie EnoruDepartment of Cardiovascular Disease, SUNY Downstate Health Science University, NY, USA.
Adedapo IluyomadeDivision of Cardiovascular Disease, University of Miami Miller School of Medicine, Miami, FL, USA.
Jonathan D MarmurDepartment of Cardiovascular Disease, SUNY Downstate Health Science University, NY, USA.
Onyedika J IlonzeDepartment of Cardiovascular Disease, Indiana University School of Medicine, IN, USA.
Senthil ThambidoraiDivision of Cardiac Electrophysiology, HCA Medical City Program, Fort Wort, TX, USA.
Hakeem AyindeDivision of Clinical Cardiac Electrophysiology, Novant Health Heart & Vascular Institute, Charlotte, NC, USA.
Icahn School of Medicine at Mount Sinai · USSUNY Downstate Health Sciences University · USIndiana University School of MedicineNovant Health · USUniversity of Miami · USUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with aortic stenosis who undergo transcatheter aortic valve replacement/transcatheter aortic valve implantation (TAVR/TAVI) experience a high incidence of pre-existing atrial fibrillation (pre-AF) and new-onset atrial fibrillation (NOAF) post-operatively. This systematic review and meta-analysis aimed to update current evidence concerning the incidence of 30-day mortality, stroke, acute kidney injury (AKI), length of stay (LOS), and early/late bleeding in patients with NOAF or pre-AF who undergo TAVR/TAVI. PubMed, Google Scholar, JSTOR, Cochrane Library, and Web of Science were searched for studies published between January 2012 and December 2020 reporting the association between NOAF/pre-AF and clinical complications after TAVR/TAVI. A total of 15 studies including 158,220 adult patients with TAVI/TAVR and NOAF or pre-AF were identified. Compared to patients in sinus rhythm, patients who developed NOAF had a higher risk of 30-day mortality, AKI, early bleeding events, extended LOS, and stroke after TAVR/TAVI (odds ratio [OR]: 3.18 [95% confidence interval [CI] 1.58, 6.40]) (OR: 3.83 [95% CI 1.18, 12.42]) (OR: 1.70 [95% CI 1.05, 2.74]) (OR: 13.96 [95% CI, 6.41, 30.40]) (OR: 2.51 [95% CI 1.59, 3.97], respectively). Compared to patients in sinus rhythm, patients with pre-AF had a higher risk of AKI and early bleeding episodes after TAVR/TAVI (OR: 2.43 [95% CI 1.10, 5.35]) (OR: 17.41 [95% CI 6.49, 46.68], respectively). Atrial fibrillation is associated with a higher risk of all primary and secondary outcomes. Specifically, NOAF but not pre-AF is associated with a higher risk of 30-day mortality, stroke, and extended LOS after TAVR/TAVI.

Indexed as

AKI, acute kidney injuryAortic stenosisAtrial fibrillationCI, confidence intervalLOS, length of stayNOAFNOAF, new-onset atrial fibrillationOR, odds ratiopre-AF, pre-existing atrial fibrillationTAVITAVI, transcatheter aortic valve implantationTAVRTAVR, transcatheter aortic valve replacement

Identifiers

PMID35146118
PMCPMC8802123
OpenAlexW4205149431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.