ArticleSSM - population health2022
Effect of childhood proximity to lead mining on late life cognition.
Article in SSM - population health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- The Impact of Childhood Cognitively Stimulating Activities on the Association between Prenatal and Early Postnatal Lead Exposure and Later Adulthood Cognitive Function.Environmental health perspectives · 2026Article
- Prenatal and Early Postnatal Lead Exposure and Later Adulthood Cognitive Function in the St. Louis Baby Tooth-Later Life Health Study.Neurology · 2026Article
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children.Science advances · 2025Article
- Linking the 1940 U.S. Census to the National Social Life, Health, and Aging Project: Novel Opportunity to Understand the Effects of Early-Life Residential Environment on Cognitive Aging.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Unmasking Lead Exposure and Neurotoxicity: Epigenetics, Extracellular Vesicles, and the Gut-Brain Connection.Indian journal of clinical biochemistry : IJCB · 2025Article
- The IPUMS Multigenerational Longitudinal Panel: Progress and Prospects.Historical methods · 2025Article
- Urinary Metal Levels, Cognitive Test Performance, and Dementia in the Multi-Ethnic Study of Atherosclerosis.JAMA network open · 2024Article
- Patterns of global burden of 13 diseases attributable to lead exposure, 1990-2019.BMC public health · 2023Article
- Childhood lead exposure is associated with lower cognitive functioning at older ages.Science advances · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
introductionLead exposure negatively affects cognitive functioning among children. However, there is limited evidence about whether exposure to lead in early life impairs later life cognitive functioning.
methodsParticipants in the prospective Wisconsin Longitudinal Study cohort (N = 8583) were linked to the 1940 Census, which was taken when they were young children. We estimated the effect of living near a lead mine in childhood on late life memory/attention and language/executive function in 2004 (mean age 64) and 2011 (mean age 71).
resultsLead-exposed children had significantly steeper memory/attention decline between 2004 and 2011 and worse language/executive function at baseline in late life. These long-term effects of lead were not mediated through adolescent IQ or late life SES and health factors. DISCUSSION: Proximity to lead mining in childhood had long-term effects on late life memory/attention decline and language/executive function, reflecting a possible latent influence of lead exposure. More research is needed to understand behavioral and biological pathways underlying this relationship.
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