Evidence map›Paper›PMID 35145803›Full record

ArticleCureus2022

A Simple Double-Spin Closed Method for Preparing Platelet-Rich Plasma.

Edilson S Machado, Fabiano P Soares, Roberta S Yamaguchi, William K Felipone, Robert Meves, Tais Amara C Souza, Roberto Topolniak, José P Caldas, Ernani V Abreu, Luiz S Rabelo Neto and 2 more

Abstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. PRP INFILTRATIONActa ortopedica brasileira · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Edilson S MachadoPain Medical Center, Regenerar, Porto Alegre, BRA.
Fabiano P SoaresPain Medical Center, Regenerar, Porto Alegre, BRA.
Roberta S YamaguchiDepartamento de Ciências Fisiológicas, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, BRA.
William K FeliponeDepartamento de Ciências Fisiológicas, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, BRA.
Robert MevesSanta Casa Spine Center, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, BRA.
Tais Amara C SouzaPain Medical Center, Regenerar, Porto Alegre, BRA.
Roberto TopolniakSanta Casa Spine Center, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, BRA.
José P CaldasPublic Health Institute, University of Porto, Porto, PRT.
Ernani V AbreuPain Medical Center, Regenerar, Porto Alegre, BRA.
Luiz S Rabelo NetoSpine Group, Hospital Ernesto Dornelles, Porto Alegre, BRA.
Pedro Vinicius S PinchemelSpine Group, Hospital Ernesto Dornelles, Porto Alegre, BRA.
Markus BredemeierServiço de Reumatologia, Hospital Nossa Senhora da Conceição, Porto Alegre, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe and analyze a new protocol for the extraction of platelet-rich plasma (PRP) for use in clinical practice and compare this technique with methods that have been previously described in the medical literature.

methodsSixteen blood samples from healthy volunteers were collected. PRP was prepared using our new double-spin technique, consisting of successive centrifugation of blood samples with two different spins, without opening the container. Descriptive analysis of cell counts in baseline and PRP samples was undertaken. Comparison between cell and platelet count in baseline and PRP samples, as well as the statistical analysis, were done.

resultsThe mean platelet concentration ratio was 3.47 (SD: 0.85; 95% CI: 3.01-3.92; range: 2.48-5.71). The baseline whole blood platelet count correlated positively to the PRP platelet count (rP

conclusionResults show a safe and easily reproducible method to obtain PRP for use in clinical daily practice.

Indexed as

double-spingrowth factorsorthobiologicsorthopedicsplatelet-rich plasmaplateletsregenerative medicine

Identifiers

PMID35145803
PMCPMC8807432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.