Evidence map›Paper›PMID 35145678›Full record

ArticleAnnals of medicine and surgery (2012)2022

Bactericidal effect of hyperbaric oxygen therapy in burn injuries.

Mendy Hatibie Oley, Maximillian Christian Oley, Louise A J Waworuntu Wewengkang, Billy Johnson Kepel, Fima Lanra Fredrik G Langi, Taat Setiadi, Deanette Michelle R Aling, Deborah Florencia Gunawan, Marcella Tirsa Tulong, Muhammad Faruk

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. An Overview of Recent Developments in the Management of Burn Injuries.International journal of molecular sciences · 2023
    Review
  7. Review
  8. In vivo and in vitro inhibition effect of propolis onAnnals of medicine and surgery (2012) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mendy Hatibie OleyPlastic Reconstructive and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Maximillian Christian OleyHyperbaric Centre Siloam Hospital, Manado, Indonesia.
Louise A J Waworuntu WewengkangClinical Microbiologist Program, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Billy Johnson KepelDepartment of Chemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Fima Lanra Fredrik G LangiDepartment Epidemiology and Biostatistics, Public Health Faculty, Sam Ratulangi University, Manado, Indonesia.
Taat SetiadiDepartment of Surgery, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Deanette Michelle R AlingHyperbaric Centre Siloam Hospital, Manado, Indonesia.
Deborah Florencia GunawanFaculty of Medicine, Sam Ratulangi University, Manado, Indonesia.
Marcella Tirsa TulongHyperbaric Centre Siloam Hospital, Manado, Indonesia.
Muhammad FarukDepartment of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Sam Ratulangi University · IDHasanuddin University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBurn injuries are frequently encountered in emergency cases and often become the port of entry for pathogens. More than 450,000 burn injuries occur annually causing nearly 3,400 deaths in the United States. The prevalence of burn injury in Indonesia is 0.7% in 2013. More than half of these According to several studies on the use of patients were treated for bacterial infections, some of which were resistant to certain antibiotics. Using hyperbaric oxygen therapy (HBOT) to treat burns has several positive effects including managing bacterial infections, as well as accelerating the wound healing process. Therefore, this study aims to prove the effectiveness of HBOT in inhibiting bacterial growth.

methodsThis is an experimental research study in rabbits using a post-test control group design. 38 rabbits were given second-degree burns on the shoulder region with a metal iron plate that has been previously heated for 3 min. Bacterial cultures were taken on days 5 and 10 after exposure to the burns. The samples were divided into two groups, HBOT and control. Statistical analyses were performed using the Mann-Whitney U method.

resultsGram-negative bacteria were the most frequently found pathogen in both groups

conclusionHBOT administration can significantly reduce bacterial growth in burn injuries.

Indexed as

Bacterial infectionBurn injuryGram-negative bacteriaHyperbaric oxygen therapyInfection

Identifiers

PMID35145678
PMCPMC8819012
OpenAlexW4210641039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.