ArticleClinical kidney journal2022
Development and internal validation of a Wasp Sting Severity Score to assess severity and indicate blood purification in persons with Asian wasp stings.
Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach From the Writing Committee of the American Society for Apheresis: The Tenth Special Issue.Journal of clinical apheresis · 2026Guideline
- Clinical characteristics of older people and risk factors for developing multiple organ dysfunction following wasp stings.European geriatric medicine · 2026Article
- Early Plasma Exchange for Multiple Organ Failure Following Massive Wasp Stings: A Case Report.Cureus · 2026Article
- Histopathological Spectrum of Acute Kidney Injury After Wasp Sting Envenomation.Kidney international reports · 2026Article
- Emergency response and clinical treatment analysis of a mass wasp sting incident involving 38 tourists: A case report.Medicine · 2026Article
- From sting to STING: role of inflammation in wasp sting induced AKI - a narrative review.BMC nephrology · 2025Review
- Clinical Management of Wasp Stings Using Large Language Models: Cross-Sectional Evaluation Study.Journal of medical Internet research · 2025Article
- Paraparesis and Paraesthesia Following A Black Ant Sting.European journal of case reports in internal medicine · 2025Article
- A prediction nomogram for mortality in patients following wasp stings: a retrospective study.Scientific reports · 2024Article
- Analysis of risk factors for acute kidney injury in children with severe wasp stings.Pediatric nephrology (Berlin, Germany) · 2024Article
- Characterization of the Hemolytic Activity of Mastoparan Family Peptides from Wasp Venoms.Toxins · 2023Article
- Wasp venom-induced acute kidney injury: current progress and prospects.Renal failure · 2023Review
- Wasp stings and plasma exchange.Clinical kidney journal · 2022Article
- Development and internal validation of a Wasp Sting Severity Score to assess severity and indicate blood purification in persons with Asian wasp stings.Clinical kidney journal · 2022Article
- Stings on wings: Proteotranscriptomic and biochemical profiling of the lesser banded hornet (Frontiers in molecular biosciences · 2022Article
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, the incidence of wasp sting has increased annually in China. Organ damage and high mortality due to mass wasp envenomation remain major challenges. Timely and appropriate medical intervention can improve survival. However, there are currently no normalized tools for early assessment of severity.
methodsThe clinical data of wasp sting patients hospitalized from 2011 to 2019 were used as a training set. Logistic regression was used to explore major risk factors for the development of a severe case of wasp sting (SC). The Wasp Sting Severity Score (WSS) was determined considering these risk factors to identify SCs and was tested in a validation dataset that was prospectively collected in 2020.
resultsThe data of 1131 wasp sting patients from 2011 to 2019 were included in the training set. Logistic regression analysis showed that tea-colored urine, number of stings, and lactate dehydrogenase and total bilirubin levels were risk factors for developing an SC. The WSS was developed considering these four risk factors, and the total possible WSS was 20 points. The WSS was tested using the validation dataset, comprising the data of 153 patients, in 2020, and we found that a WSS ≥3 points was an important indication for blood purification, with a sensitivity of 71.9%, specificity of 92.6% and an area under the curve of 0.918 (95% confidence interval 0.873-0.962). Among patients with more than 30 stings, mortality in those who underwent plasma exchange (PE) within 24 h after admission was significantly lower than that in those who did not receive PE treatment (14.3% versus 46.9%, P = 0.003). However, continuous venovenous hemofiltration (CVVH) (P = 0.317) and hemoperfusion (HP) (P = 0.869) did not significantly reduce mortality.
conclusionsPatients with WSS scores ≥3 should be considered for blood purification as early as possible in addition to routine treatment. In addition, PE is better than CVVH and HP at reducing mortality in patients suffering from severe wasp stings.
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