Evidence map›Paper›PMID 35145634›Full record

ArticleClinical kidney journal2022

Local anesthetics for the Nephrologist.

Nupur N Uppal, Mital Jhaveri, Susana Hong, Linda Shore-Lesserson, Kenar D Jhaveri, Hassan Izzedine

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Anesthesia for uterine transplantation.Anesthesia and pain medicine · 2026
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Migraine Management in Medically Complex Patients: a Narrative Review.Current neurology and neuroscience reports · 2024
    Review
  13. Outcomes of Regional Block in Revision Total Joint Arthroplasty for Prosthetic Joint Infection.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024
    Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nupur N UppalDivision of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Great Neck, NY, USA.
Mital JhaveriDepartment of Pharmacy, Queens Hospital Center, Jamaica, NY, USA.
Susana HongDivision of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Great Neck, NY, USA.
Linda Shore-LessersonDepartment of Anesthesiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Manhasset, NY, USA.
Kenar D JhaveriDivision of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Great Neck, NY, USA.
Hassan IzzedineDepartment of Nephrology, Peupliers Private Hospital, Ramsay Générale de Santé, Paris, France.ORCID https://orcid.org/0000-0001-6249-9837
Northwell Health · USGénérale de Santé · FRQueens Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several specialists in medicine use local anesthetics. In patients with kidney disease, these agents are used during catheter insertions for hemodialysis and peritoneal dialysis, arteriovenous fistula and graft procedures, kidney transplantation, parathyroidectomy, kidney biopsies, and dental and skin procedures. Patients on chronic hemodialysis use a topical application prior to use of needles for arteriovenous fistula cannulation before starting dialysis. They are also used to manage acute and chronic pain conditions, in regional nerve blockade and in multi-modal enhanced recovery protocols. Despite their frequent use by both physicians and patients, data on the use of local anesthetics in patients with kidney impairment are not well reported. This review will summarize the use of local anesthetics in chronic kidney disease, describe their pharmacology and the impact of lower estimated glomerular filtration rate on their pharmacokinetics, and suggest dose regulation in those with kidney dysfunction.

Indexed as

chronic kidney diseaselocal anestheticspharmacology

Identifiers

PMID35145634
PMCPMC8824772
OpenAlexW3182882651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.