Evidence map›Paper›PMID 35145548›Full record

ArticleFrontiers in genetics2022

Further Delineation of the Spectrum of XMEN Disease in Six Chinese Pediatric Patients.

Xiaomin Peng, Yi Lu, Huijun Wang, Bingbing Wu, Mingyu Gan, Suzhen Xu, Deyi Zhuang, Jianshe Wang, Jinqiao Sun, Xiaochuan Wang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Case Report: NovelFrontiers in immunology · 2026
    Article
  3. Article
  4. Effects of two different variants in theFrontiers in immunology · 2025
    Article
  5. Adult-onset neurodegeneration in XMEN disease.Journal of neuroimmunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xiaomin PengCenter for Molecular Medicine of Children's Hospital of Fudan University and National Children's Medical Center, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Yi LuCenter for Pediatric Liver Diseases, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Huijun WangCenter for Molecular Medicine, Key Laboratory of Birth Defects, Pediatrics Research Institute, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Bingbing WuCenter for Molecular Medicine, Key Laboratory of Birth Defects, Pediatrics Research Institute, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Mingyu GanCenter for Molecular Medicine, Key Laboratory of Birth Defects, Pediatrics Research Institute, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Suzhen XuCenter for Molecular Medicine, Key Laboratory of Birth Defects, Pediatrics Research Institute, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Deyi ZhuangDepartment of Pediatrics, Xiamen Children's Hospital, Xiamen, China.
Jianshe WangCenter for Pediatric Liver Diseases, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Jinqiao SunDepartment of Clinical Immunology, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Xiaochuan WangDepartment of Clinical Immunology, Children's Hospital of Fudan University and National Children's Medical Center, Shanghai, China.
Wenhao ZhouCenter for Molecular Medicine of Children's Hospital of Fudan University and National Children's Medical Center, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Children's Hospital of Fudan University · CNChildren’s Hospital of Fudan University Xiamen Branch · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-linked MAGT1 deficiency with increased susceptibility to EBV-infection and N-linked glycosylation defect (XMEN) disease is a primary immunodeficiency caused by loss-of-function variants in the

Indexed as

elevated liver enzymesgenetic testingimmunodeficiencyMAGT1 geneXMEN

Identifiers

PMID35145548
PMCPMC8821886
OpenAlexW4210538199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.