SynthesisFrontiers in neurology2021
Cigarette Smoking and Risk of Different Pathologic Types of Stroke: A Systematic Review and Dose-Response Meta-Analysis.
Synthesis in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
- Proteome-wide genetic analyses identify ASGR1 as a potential biomarker linking smoking with ischemic heart disease.Nature cardiovascular research · 2026Article
- Nicotine-containing products and the cardiovascular system: mechanisms and global health implications.Nature reviews. Cardiology · 2026Review
- Impact of preoperative smoking on outcomes of endoscopic transsphenoidal surgery for pituitary tumor.Endocrine · 2026Article
- Depression trajectory modifies the association between estimated glucose disposal rate and incident stroke: a prospective cohort study.BMC cardiovascular disorders · 2026Article
- Enhancing Cardiopulmonary Function Through Spasticity Reduction-Effects of Botulinum Toxin A After Stroke: A Prospective Before-After Study.Medicina (Kaunas, Lithuania) · 2026Article
- Health effects of black and blond tobacco: a comparative analysis on smoking-related diseases with emphasis on bronchitis and COPD.Frontiers in public health · 2026Article
- Ivermectin attenuates nicotine-induced reward-like behaviors in mice.Biomolecules & biomedicine · 2025Article
- Assessment of hearing function and prevalence of hearing impairment among stroke patients and its relationship to leisure and social activity limitation: a nationwide population-based study.Journal of medicine and life · 2025Article
- Stroke risk in ADPKD patients treated by dialysis: a retrospective study.Clinical kidney journal · 2025Article
- Do CRP gene variants and smoking elevate recurrent stroke risk in minor ischemic stroke patients?European journal of medical research · 2025Article
- The PLANS model predicts recurrent strokes in patients with minor ischemic strokes.Scientific reports · 2025Article
- Case fatality rate and associated factors of mortality among first-ever stroke patients: a prospective cohort study in Erbil City, Iraq.The Pan African medical journal · 2025Article
- Article
- Evaluating machine learning models for stroke prediction based on clinical variables.Frontiers in neurology · 2025Article
- The interaction between diet quality and cigarette smoking on the incidence of hypertension, stroke, cardiovascular diseases, and all-cause mortality.Scientific reports · 2024Article
- Examining the influence of global smoking prevalence on stroke mortality: insights from 27 countries across income strata.BMC public health · 2024Article
- Smoke Signals: Unraveling the Paradoxical Impact of Smoking on Stroke Prognosis and Treatment Efficacy.Cureus · 2024Review
- Global burden of stroke attributable to secondhand smoke in 204 countries and territories from 1990 to 2019: analysis of the global burden of disease study.Frontiers in neurology · 2024Article
- Assessing tobacco-related ischemic stroke in Pakistan (1990-2019): Insights from the Global Burden of Disease Study.Tobacco induced diseases · 2024Article
- Global, regional, and national burden of ischemic stroke attributable to active smoking, 1990-2021.Tobacco induced diseases · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesTo quantify the association of cigarette smoking, including cigarettes per day and quitting duration, with the risk of different types of stroke morbidity and mortality in the general population, and to clarify the shape of the dose-response relations. STUDY SELECTION: Prospective cohort studies and reported on the association between smoking, quitting and the incidence or mortality of stroke were included. DATA EXTRACTION AND SYNTHESIS: All available data were converted uniformly to odds ratios (ORs) and were pooled using random-effects meta-analysis with inverse variance weighting. A dose-response meta-analysis was performed to explore the quantitative relationship between different smoking characteristics and the risk of different pathologic types of stroke incidence.
resultsTwenty-five studies with 3,734,216 individuals were included. Compared to never smokers, the pooled ORs of stroke morbidity and mortality were 1.45 (1.24-1.70) and 1.44 (1.23-1.67) among ever smokers and 1.90 (1.55-2.34) and 1.70 (1.45-1.98) among current smokers. The risk of different pathologic types of stroke was also increased among ever and current smokers. There was a significant non-linear dose-response association between the number of cigarette smoking and the risk of stroke incidence. Comparing no smoking, the ORs for smoking five and 35 cigarettes per day were 1.44 (1.35-1.53) and 1.86 (1.71-2.02). Other pathologic types of stroke have a similar dose-response relationship. There was also non-linear dose-response association between the length of time since quitting and risk of stroke. The risk of stroke decreased significantly after quitting for 3 years [OR = 0.56 (0.42-0.74)].
conclusionThe risk of different types of stroke among smokers is remarkably high. Our findings revealed a more detailed dose-response relationship and have important implications for developing smoking control strategies for stroke prevention. SYSTEMATIC REVIEW REGISTRATION: https://inplasy.com/inplasy-2020-6-0062/, identifier: INPLASY202060062.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.