Evidence map›Paper›PMID 35145376›Full record

ArticleFrontiers in neuroscience2021

Fluid-Attenuated Inversion Recovery Vascular Hyperintensity as a Potential Predictor for the Prognosis of Acute Stroke Patients After Intravenous Thrombolysis.

Lin Zhu, Fuping Jiang, Meng Wang, Qian Zhai, Qing Zhang, Feng Wang, Xuqiang Mao, Nihong Chen, Junshan Zhou, Guangjun Xi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lin ZhuDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Fuping JiangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Meng WangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Qian ZhaiDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Qing ZhangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Feng WangDepartment of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Xuqiang MaoDepartment of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Nihong ChenDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Junshan ZhouDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Guangjun XiDepartment of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Yachen ShiDepartment of Neurology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Nanjing Medical University · CNWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluid-attenuated inversion recovery vascular hyperintensity (FVH) can reflect the collateral status, which may be a valuable indicator to predict the functional outcome of acute stroke (AS) patients.

methodsA total of 190 AS patients with large vessel occlusion (LVO) were retrospectively investigated. All patients completed a 6-month follow-up and their modified Rankin Scale (mRS) scores were recorded at 1, 3, and 6 months after intravenous thrombolysis (IVT). Based on their mRS at 3 months, patients were divided into two groups: poor prognosis (131 patients; 68.9% of all subjects) and favorable prognosis (59 patients; 31.1% of all subjects). The death records of 28 patients were also analyzed in the poor prognosis group.

results(1) Univariate and multivariate analyses showed that the higher National Institutes of Health Stroke Scale (NIHSS) score at admission, higher fasting blood glucose, and lower FVH score were independent risk factors to predict the poor prognosis of IVT. (2) Survival analysis indicated that FVH score was the only baseline factor to predict the 6-month survival after IVT. (3) Baseline FVH score had great prediction performance for the prognosis of IVT (area under the curve = 0.853). (4) Baseline FVH score were negatively correlated with the NIHSS score at discharge and mRS score at 1, 3, and 6 months.

conclusionAmong various baseline clinical factors, only the FVH score might have implications for 3-month outcome and 6-month survival of AS patients after IVT. Baseline FVH score showed great potential to predict the prognosis of the AS patients.

Indexed as

acute strokefluid-attenuated inversion recovery vascular hyperintensityintravenous thrombolysisprognosissurvival

Identifiers

PMID35145376
PMCPMC8823327
OpenAlexW4207003959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.