Evidence map›Paper›PMID 35145353›Full record

ArticleDose-response : a publication of International Hormesis Society

Identification of Ascorbic Acid and Gallic Acid as Novel Inhibitors of Secreted Frizzled-Related Protein for the Treatment of Obesity-Induced Type 2 Diabetes.

Shazia Anwer Bukhari, Aysha Yasmin, Azhar Rasul, Muhammad Asif Zahoor, Ghulam Mustafa, Dunia A Al Farraj, Noura M Darwish, Lotfi Aleya, Asim Rehman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Shazia Anwer BukhariDepartment of Biochemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Aysha YasminDepartment of Biochemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Azhar RasulDepartment of Zoology, Government College University Faisalabad, Faisalabad, Pakistan.
Muhammad Asif ZahoorDepartment of Microbiology, Government College University, Faisalabad, Pakistan.
Ghulam MustafaDepartment of Biochemistry, Government College University Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0001-6510-6496
Dunia A Al FarrajFaculty of science, Ain Shams University, Biochemistry Department, Cairo, Egypt.
Noura M DarwishFaculty of science, Ain Shams University, Biochemistry Department, Cairo, Egypt.
Lotfi AleyaLaboratoire Chrono-Environnement, CNRS6249, Universite de Bourgogne Franche-Comte, Besancon, France.
Asim RehmanDepartment of Biochemistry, Government College University Faisalabad, Faisalabad, Pakistan.
Government College University, Faisalabad · PKAin Shams University · EGCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2D) has been reported as major public health issue rising at an alarming rate worldwide, and obesity is the leading risk factor for the development of T2D. Secreted frizzled-related protein 4 (

Indexed as

biomarkerdiet-induced diabetic miceHepG2 (NT)high fat dietmolecular docking

Identifiers

PMID35145353
PMCPMC8822024
OpenAlexW4212864537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.