Evidence map›Paper›PMID 35145190›Full record

ArticleScientific reports2022

Molecular characterization of echovirus 9 strains isolated from hand-foot-and-mouth disease in Kunming, Yunnan Province, China.

Ming Zhang, Wei Guo, Danhan Xu, Changzeng Feng, Guohong Bao, Hao Sun, Zhaoqing Yang, Shaohui Ma

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Genetic Diversity of Human Enterovirus in Kazakhstan, during 2022.International journal of microbiology · 2024
    Article
  3. Article
  4. Article
  5. Genetic Characteristics and Phylogeographic Dynamics of Echovirus.Journal of microbiology (Seoul, Korea) · 2023
    Article
  6. Hand, Foot, and Mouth Disease: A Narrative Review.Recent advances in inflammation & allergy drug discovery · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ming Zhang *Institute of Medical Biology, Peking Union Medical College, Chinese Academy of Medical Sciences, Kunming, 650118, People's Republic of China.
Wei Guo *Institute of Medical Biology, Peking Union Medical College, Chinese Academy of Medical Sciences, Kunming, 650118, People's Republic of China.
Danhan XuInstitute of Medical Biology, Peking Union Medical College, Chinese Academy of Medical Sciences, Kunming, 650118, People's Republic of China.
Changzeng FengInstitute of Medical Biology, Peking Union Medical College, Chinese Academy of Medical Sciences, Kunming, 650118, People's Republic of China.
Guohong BaoFirst People's Hospital of Yunnan Province, Kunming, People's Republic of China.
Hao SunInstitute of Medical Biology, Peking Union Medical College, Chinese Academy of Medical Sciences, Kunming, 650118, People's Republic of China.
Zhaoqing YangInstitute of Medical Biology, Peking Union Medical College, Chinese Academy of Medical Sciences, Kunming, 650118, People's Republic of China.
Shaohui MaInstitute of Medical Biology, Peking Union Medical College, Chinese Academy of Medical Sciences, Kunming, 650118, People's Republic of China. shaohuima70@hotmail.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNFirst People's Hospital of Yunnan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Echovirus 9 (E9) belongs to the species Enterovirus B. So far, 12 whole genome sequences of E9 are available in GenBank. In this study, we determined the whole genomic sequences of five E9 strains isolated from the stools of patients with hand-foot-and-mouth disease in Kunming, Yunnan Province, China, in 2019. Their nucleotide and amino acid sequences shared 80.8-80.9% and 96.4-96.8% identity with the prototype Hill strain, respectively, and shared 99.3-99.9% and 99.1-99.8% mutual identity, respectively. Recombination analyses revealed that intertype recombination had occurred in the 2C and 3D regions of the five Yunnan E9 strains with coxsackieviruses B5 and B4, respectively. This study augmented the whole genome sequences of E9 in the GenBank database and extended the molecular characterization of this virus in China.

Indexed as

Child, PreschoolChinaDatabases, Nucleic AcidEchovirus 9Enterovirus B, HumanGenome, ViralHand, Foot and Mouth DiseaseHumansInfantPhylogenyRecombination, GeneticWhole Genome Sequencing

Identifiers

PMID35145190
PMCPMC8831506
OpenAlexW4211097596

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.