Evidence map›Paper›PMID 35145030›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Somatostatin-type and allatostatin-C-type neuropeptides are paralogous and have opposing myoregulatory roles in an echinoderm.

Ya Zhang, Luis Alfonso Yañez-Guerra, Ana B Tinoco, Nayeli Escudero Castelán, Michaela Egertová, Maurice R Elphick

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Discovery and functional characterization of a bombesin-type neuropeptide signaling system in an invertebrate.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ya ZhangSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, E1 4NS, United Kingdom.ORCID 0000-0002-2158-0660
Luis Alfonso Yañez-GuerraSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, E1 4NS, United Kingdom.ORCID 0000-0002-2523-1310
Ana B TinocoSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, E1 4NS, United Kingdom.ORCID 0000-0003-0525-4475
Nayeli Escudero CastelánSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, E1 4NS, United Kingdom.ORCID 0000-0001-8443-9085
Michaela EgertováSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, E1 4NS, United Kingdom.
Maurice R ElphickSchool of Biological and Behavioural Sciences, Queen Mary University of London, London, E1 4NS, United Kingdom m.r.elphick@qmul.ac.uk.ORCID 0000-0002-9169-0048
Queen Mary University of London · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Somatostatin (SS) and allatostatin-C (ASTC) are inhibitory neuropeptides in chordates and protostomes, respectively, which hitherto were identified as orthologs. However, echinoderms have two SS/ASTC-type neuropeptides (SS1 and SS2), and here, our analysis of sequence data indicates that SS1 is an ortholog of ASTC and SS2 is an ortholog of SS. The occurrence of both SS-type and ASTC-type neuropeptides in echinoderms provides a unique context to compare their physiological roles. Investigation of the expression and actions of the ASTC-type neuropeptide ArSS1 in the starfish

Indexed as

Amino Acid SequenceAnimalsGene Expression RegulationMusclesNeuropeptidesStarfishNeuropeptidesallatostatin-Cevolutionneuropeptidesomatostatinstarfish

Identifiers

PMID35145030
PMCPMC8851493
OpenAlexW4211213944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.