Evidence map›Paper›PMID 35145016›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

MIRD Pamphlet No. 27: MIRDcell V3, a Revised Software Tool for Multicellular Dosimetry and Bioeffect Modeling.

Sumudu Katugampola, Jianchao Wang, Alex Rosen, Roger W Howell, SNMMI MIRD committee

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. In Vitro Radiobiological Evaluation of [Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Review
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  6. Preirradiation of Spheroids withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  7. Article
  8. Review
  9. MIRD Pamphlet No. 31: MIRDcell V4-Artificial Intelligence Tools to Formulate Optimized Radiopharmaceutical Cocktails for Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Palladium-103 (Theranostics · 2024
    Article
  15. Article
  16. Article
  17. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  18. Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  19. Article
  20. Marshalling the Potential of Auger Electron Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sumudu KatugampolaDivision of Radiation Research, Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey.
Jianchao WangDivision of Radiation Research, Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey.
Alex RosenDivision of Radiation Research, Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey.
Roger W HowellDivision of Radiation Research, Department of Radiology, New Jersey Medical School, Rutgers University, Newark, New Jersey rhowell@rutgers.edu.
SNMMI MIRD committee
Rutgers New Jersey Medical School

Funding

MIRDcell Version 3R01CA245139 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Roger W. Howell · 2020 to 2026
$1.8M
Radiation induced bystander effects in radium-223 therapyR01CA198073 · NCI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI AZZAM, EDOUARD I, HOWELL, ROGER W. · 2015 to 2018
$1.3M
NCI NIH HHS R01 CA198073NCI NIH HHS R01 CA245139
6 · The paper itself

Abstract

Radiopharmaceutical therapy is growing rapidly. However, yet to be addressed is the implementation of methods to plan treatments for circulating tumor cells, disseminated tumor cells, and micrometastases. Given the capacity of radiopharmaceuticals to specifically target and kill single cells and multicellular clusters, a quality not available in chemotherapy and external-beam radiation therapy, it is important to develop dosimetry and bioeffect modeling tools that can inform radiopharmaceutical design and predict their effect on microscopic disease. This pamphlet describes a new version of MIRDcell, a software tool that was initially released by the MIRD committee several years ago.

Indexed as

PamphletsRadiopharmaceuticalsMonte Carlo MethodRadiometrySoftwareRadiopharmaceuticalscell survivaldosimetrymulticellular clusternonuniform activity distributionradionuclide

Identifiers

PMID35145016
PMCPMC9454469
OpenAlexW4210983759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.