Evidence map›Paper›PMID 35144998›Full record

ArticleImmunoHorizons2022

IL-17 Receptor Signaling through IL-17A or IL-17F Is Sufficient to Maintain Innate Response and Control of

Beverly R E A Dixon, Tiffany J Lee, Diana C Contreras Healey, Jing Li, Jeremy A Goettel, M Blanca Piazuelo, Holly M Scott Algood

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Managing dangerous liaisons: lessons fromJournal of bacteriology · 2026
    Review
  2. Gastric Inflammation Impacts Serotonin Secretion in a Mouse Model ofInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Beverly R E A DixonDepartment of Medicine, Division of Infectious Disease, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Tiffany J LeeDepartment of Medicine, Division of Infectious Disease, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Diana C Contreras HealeyDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Jing LiDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Jeremy A GoettelDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0002-0749-2357
M Blanca PiazueloVanderbilt Institute of Infection, Immunity, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.
Holly M Scott AlgoodDepartment of Medicine, Division of Infectious Disease, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN; holly.m.algood@vumc.org.ORCID 0000-0003-3735-4649
Vanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
The role of Th17 cytokines in H.pylori infectionI01BX000915 · VA · VETERANS HEALTH ADMINISTRATION · PI HOLLY Marie Scott ALGOOD · 2011 to 2026
–
BLRD VA I01 BX000915NCI NIH HHS P30 CA068485NIDDK NIH HHS P30 DK058404NIDDK NIH HHS U24 DK059637
6 · The paper itself

Abstract

IL-17R signaling is required for control of extracellular pathogens and is also implicated in development of chronic inflammatory processes. The response to the human pathogen

Indexed as

Helicobacter InfectionsHelicobacter pyloriAnimalsInflammationInterleukin-17MiceReceptors, Interleukin-17Il17a protein, mouseIl17f protein, mouseIl17ra protein, mouseInterleukin-17Receptors, Interleukin-17

Identifiers

PMID35144998
PMCPMC9364271
OpenAlexW4211257323

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.