Evidence map›Paper›PMID 35144959›Full record

ArticleBMJ open2022

Impact of one and two human papillomavirus (HPV) vaccine doses on community-level HPV prevalence in South African adolescent girls: study protocol and rationale for a pragmatic before-after design.

Dorothy Machalek, Helen Rees, Admire Chikandiwa, Richard Munthali, Danielle Travill, Zizipho Mbulawa, Kathy Petoumenos, Sinead Delany-Moretlwe, John Kaldor, HOPE Study team

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Strategic approaches for global cervical cancer elimination: An update review and call for national action.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 5 countries.

Dorothy MachalekKirby Institute, University of New South Wales-Kensington Campus, Sydney, New South Wales, Australia.ORCID 0000-0002-4101-8085
Helen ReesWits RHI, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.
Admire ChikandiwaWits RHI, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.
Richard MunthaliWits RHI, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.
Danielle TravillWits RHI, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.
Zizipho MbulawaUCT-MRC Clinical Gynaecological Cancer Research Centre, University of Cape Town, Rondebosch, Western Cape, South Africa.
Kathy PetoumenosKirby Institute, University of New South Wales-Kensington Campus, Sydney, New South Wales, Australia.
Sinead Delany-MoretlweWits RHI, University of the Witwatersrand, Johannesburg, Gauteng, South Africa sdelany@wrhi.ac.za.
John KaldorKirby Institute, University of New South Wales-Kensington Campus, Sydney, New South Wales, Australia.
HOPE Study team
University of the Witwatersrand · ZAUNSW Sydney · AURoyal Women's Hospital · AUUniversity of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVaccines against human papillomavirus (HPV) are the key to controlling cervical cancer in low/middle-income countries (LMICs) where incidence is highest, but there have been limited data from these settings on programme impact on HPV prevalence, and none in a population with endemic HIV infection. Furthermore, for many LMICs, the currently recommended two-dose schedule is difficult to deliver at scale, so there is mounting interest in a single-dose schedule. METHODS AND ANALYSIS: The ETHICS AND DISSEMINATION: The project was approved by the University of the Witwatersrand Human Research Ethics Committee (HREC #181005), and the University of New South Wales HREC (#181-005). Findings will be disseminated through peer-reviewed journals, scientific meetings, reports and community forums.

Indexed as

AlphapapillomavirusHIV InfectionsPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsAdolescentCross-Sectional StudiesFemaleHumansPapillomaviridaePrevalenceSouth AfricaVaccinationPapillomavirus Vaccinesepidemiologyinfection controlpublic health

Identifiers

PMID35144959
PMCPMC8845310
OpenAlexW4211255725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.