ArticleeLife2022
Genetic integration of behavioural and endocrine components of the stress response.
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Fish adapt and dynamically avoid an approaching robotic fish across repeated exposures.Scientific reports · 2026Article
- Resistance of AdultIntegrative organismal biology (Oxford, England) · 2026Article
- A framework for a low-cost system of automated gate control in assays of spatial cognition in fishes.Journal of fish biology · 2025Article
- Circles of deception: the Ebbinghaus illusion from fish to birds.Frontiers in psychology · 2025Article
- Early impact of domestication on aggressiveness, activity, and stress behaviors in zebrafish (Danio rerio) using mirror test and automated videotracking.Scientific reports · 2024Article
- Endocrine flexibility can facilitate or constrain the ability to cope with global change.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- HPA flexibility andPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Among-individual behavioural variation in the ornamental red cherry shrimp,Ecology and evolution · 2024Article
- Trait sensitivity to stress and cognitive bias processes in fish: A brief overview.Personality neuroscience · 2024Review
- Article
- Shared community effects and the non-genetic maternal environment shape cortisol levels in wild chimpanzees.Communications biology · 2023Article
- Article
- Exploiting animal personality to reduce chronic stress in captive fish populations.Frontiers in veterinary science · 2022Article
- Article
- A reinvestigation of cognitive styles in sticklebacks: decision success varies with behavioral type.Behavioral ecology : official journal of the International Society for Behavioral EcologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
The vertebrate stress response comprises a suite of behavioural and physiological traits that must be functionally integrated to ensure organisms cope adaptively with acute stressors. Natural selection should favour functional integration, leading to a prediction of genetic integration of these traits. Despite the implications of such genetic integration for our understanding of human and animal health, as well as evolutionary responses to natural and anthropogenic stressors, formal quantitative genetic tests of this prediction are lacking. Here, we demonstrate that acute stress response components in Trinidadian guppies are both heritable and integrated on the major axis of genetic covariation. This integration could either facilitate or constrain evolutionary responses to selection, depending upon the alignment of selection with this axis. Such integration also suggests artificial selection on the genetically correlated behavioural responses to stress could offer a viable non-invasive route to the improvement of health and welfare in captive animal populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.