Evidence map›Paper›PMID 35144690›Full record

ArticleJournal of animal science and biotechnology2022

Ryanodine receptor RyR1-mediated elevation of Ca

Kai Qiu, Yubo Wang, Doudou Xu, Linjuan He, Xin Zhang, Enfa Yan, Lu Wang, Jingdong Yin

Open access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. RYR1Journal of translational medicine · 2026
    Article
  2. Effects ofAnimals : an open access journal from MDPI · 2025
    Article
  3. Biomolecules · 2025
    Article
  4. Sperm Motility Is Modulated by FInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kai Qiu *State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Yubo Wang *State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Doudou XuState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Linjuan HeState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Xin ZhangState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Enfa YanState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Lu WangState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Jingdong YinState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. yinjd@cau.edu.cn.ORCID http://orcid.org/0000-0003-4623-0568
China Agricultural University · CNChinese Academy of Agricultural Sciences · CN

Funding

National key research and development program of China 2018YFD0500402National Natural Science Foundation of China 31672431National Natural Science Foundation of China 31790412
6 · The paper itself

Abstract

backgroundCytosolic Ca

resultsIn the present study, both RyR1-knockdown myoblasts and CRISPR/Cas9-based RyR1-knockout myoblasts were employed to explore the role of RyR1 in myogenic differentiation, myotube formation as well as the potential mechanism of RyR1-related myopathies. We observed that RyR1 expression was dramatically increased during the late stage of myogenic differentiation, accompanied by significantly elevated cytoplasmic Ca

conclusionsTherefore, we concluded that Ca

Indexed as

ApoptosisCa2+ homeostasisEndoplasmic reticulum stressMyoblast fusionMyogenic differentiationRyR1 knockout

Identifiers

PMID35144690
PMCPMC8832842
OpenAlexW4211155210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.