Evidence map›Paper›PMID 35144660›Full record

ReviewChinese medicine2022

Mineral medicine: from traditional drugs to multifunctional delivery systems.

Xiaoqing Zhong, Zhenning Di, Yuanxin Xu, Qifan Liang, Kuanhan Feng, Yuting Zhang, Liuqing Di, Ruoning Wang

Open access · goldAbstract readReview
In one paragraph

Review in Chinese medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Epigallocatechin Gallate Derivative YRecent patents on anti-cancer drug discovery · 2025
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaoqing Zhong *College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Zhenning Di *College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yuanxin Xu *College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Qifan LiangCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Kuanhan FengCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yuting ZhangCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Liuqing DiCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. diliuqing@nujcm.edu.cn.
Ruoning WangCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. ruoningw@njucm.edu.cn.ORCID http://orcid.org/0000-0001-7466-9602
Nanjing University of Chinese Medicine · CN

Funding

National Natural Science Foundation of China 81903557National Natural Science Foundation of China 82074024
6 · The paper itself

Abstract

Mineral drugs are an important constituent of traditional Chinese medicine (TCM). Taking minerals that contain heavy metals as drugs is a very national characteristic part of TCM. However, the safety and scientific nature of mineral drugs are controversial owing to their heavy metals and strong toxicity. In 2000, the Food and Drug Administration (FDA) authorized arsenic trioxide (ATO) as first-line therapy for acute promyelocytic leukemia. This makes the development and utilization of mineral drugs become a research hotspot. The development of nanomedicine has found a great prospect of mineral drugs in nano-delivery carriers. And that will hold promise to address the numerous biological barriers facing mineral drug formulations. However, the studies on mineral drugs in the delivery system are few at present. There is also a lack of a detailed description of mineral drug delivery systems. In this review, the advanced strategies of mineral drug delivery systems in tumor therapy are summarized. In addition, the therapeutic advantages and research progress of novel mineral drug delivery systems are also discussed. Here, we hope that this will provide a useful reference for the design and application of new mineral drug delivery systems.

Indexed as

Active ingredientMineral drugNovel drug delivery systemTraditional preparation

Identifiers

PMID35144660
PMCPMC8830990
OpenAlexW4211131951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.