Evidence map›Paper›PMID 35144644›Full record

ArticleBMC research notes2022

Childhood glaucoma registry in Germany: initial database, clinical care and research (pilot study).

Fidan A Aghayeva, Alexander K Schuster, Heidi Diel, Panagiotis Chronopoulos, Felix M Wagner, Franz Grehn, Nina Pirlich, Susann Schweiger, Norbert Pfeiffer, Esther M Hoffmann

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Fidan A AghayevaDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Alexander K SchusterDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Heidi DielDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Panagiotis ChronopoulosDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Felix M WagnerDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Franz GrehnDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Nina PirlichDepartment of Anaesthesiology, University Medical Center of the Johannes Gutenberg, University Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Susann SchweigerInstitute of Human Genetics, University Medical Centre of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Norbert PfeifferDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany.
Esther M HoffmannDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany. ehoffman@uni-mainz.de.ORCID http://orcid.org/0000-0002-0949-4268
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this prospective pilot study is to establish an initial database to register patients diagnosed with different types of childhood glaucoma and the set-up of a national registry for childhood glaucoma (ReCG) in Germany. 28 children with different types of diagnosed childhood glaucoma, who were admitted and treated at the Childhood Glaucoma Center of the University Medical Center Mainz, Germany were included. Main outcome measures were the type of childhood glaucoma, mean intraocular pressure (IOP) and genetic data of the patients.

resultsThe documents and questionnaires for each individual included: informed consent form of the parents, medical history form of the child, patient's gestational history questionnaire and general anesthesia examination form. Primary congenital and secondary childhood glaucoma were revealed in 11 (39%) and 17 (61%) patients, respectively. The mean IOP measured with Perkins tonometer in all patients under general anesthesia at the time of inclusion was 17.5 ± 11.8 mmHg in the right and 17 ± 8.9 mmHg in the left eyes. In 33% of children with glaucoma mutations in the CYP1B1, FOXC1, LTBP2 and TEK genes were found. The development of specific questionnaires for childhood glaucoma provides detailed baseline data to establish a ReCG in Germany for the first time.

Indexed as

GlaucomaIntraocular PressureChildGermanyHumansPilot ProjectsProspective StudiesRegistriesChildhood glaucoma registryCongenital glaucomaConsanguinityGenetic examinationQuestionnaire

Identifiers

PMID35144644
PMCPMC8830121
OpenAlexW4211029471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.