Evidence map›Paper›PMID 35144632›Full record

ArticleAnnals of clinical microbiology and antimicrobials2022

Population snapshot of the extended-spectrum β-lactamase-producing Escherichia coli invasive strains isolated from a Hungarian hospital.

Kinga Tóth, Ákos Tóth, Katalin Kamotsay, Viktória Németh, Dóra Szabó

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. High clonal diversity, resistome, and virulome ofFrontiers in microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Genomic Epidemiology of C2/H30Rx and C1-M27 Subclades ofAntibiotics (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Extended-spectrum beta-lactamase inOne health (Amsterdam, Netherlands) · 2023
    Review
  9. Hospital and community wastewater as a source of multidrug-resistant ESBL-producingFrontiers in cellular and infection microbiology · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kinga TóthInstitute of Medical Microbiology, Semmelweis University, Budapest, Hungary. toth.kinga@phd.semmelweis.hu.ORCID http://orcid.org/0000-0002-6352-777X
Ákos TóthDepartment of Bacteriology, Mycology, and Parasitology, National Public Health Center, Budapest, Hungary.
Katalin KamotsayCentral Microbiology Laboratory, Central Hospital of Southern Pest National Institute of Hematology and Infectious Disease, Budapest, Hungary.
Viktória NémethCentral Microbiology Laboratory, Central Hospital of Southern Pest National Institute of Hematology and Infectious Disease, Budapest, Hungary.
Dóra SzabóInstitute of Medical Microbiology, Semmelweis University, Budapest, Hungary.
Semmelweis University · HUNational Public Health and Medical Officer Service · HU

Funding

Hungarian Scientific Research Fund 108481
6 · The paper itself

Abstract

backgroundThis study was carried out to determine the prevalence and the genetic background of extended-spectrum β-lactamase-producing Escherichia coli invasive isolates obtained from a tertiary-care hospital in Budapest, Hungary.

methodsBetween October-November 2018, all invasive ESBL-producing E. coli isolates were collected from Central Hospital of Southern Pest. The antimicrobial susceptibility testing was performed according to the EUCAST guidelines. The possible clonal relationships were investigated by core genome (cg)MLST (SeqSphere +) using whole-genome sequencing (WGS) data of isolates obtained from Illumina 251-bp paired-end sequencing. From WGS data acquired antimicrobial resistance genes, virulence genes and replicon types were retrieved using ResFinder3.1, PlasmidFinder2.1, pMLST-2.0, VirulenceFinder2.0 and Virulence Factors Database online tools.

resultsOverall, six E. coli isolates proved to be resistant to third-generation cephalosporins and ESBL-producers in the study period. Full genome sequence analysis showed that five E. coli isolates belonged to the ST131 clone: two to C1-M27 subclade with bla

conclusionsOut of six ESBL-producing E. coli, five belonged to the ST131 clone. This study indicates, that the C2/H30Rx and C1-M27 subclades of the ST131 appear to be the dominant clones collected in a Hungarian hospital.

Indexed as

Anti-Bacterial Agentsbeta-LactamasesEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsHospitalsHumansHungaryIncidenceMultilocus Sequence TypingPrevalenceAnti-Bacterial Agentsbeta-LactamasesEscherichia coli ProteinsBla CTX-M-15Bla CTX-M-27C1-M27Escherichia coliExtended-spectrum β-lactamaseST131

Identifiers

PMID35144632
PMCPMC8829994
OpenAlexW4224957492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.