Evidence map›Paper›PMID 35144564›Full record

ArticleBMC ophthalmology2022

Relapsed acute myeloid leukemia presenting as conjunctival myeloid sarcoma: a case report.

Joong Hyun Park, Yengwoo Son, Joon Young Hyon, Ji Yun Lee, Hyun Sun Jeon

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Enhanced Imaging of Ocular Surface Lesions.Journal of clinical medicine · 2025
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Joong Hyun Park *Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Yengwoo Son *Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Joon Young HyonDepartment of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Ji Yun LeeDivision of Hematology-Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Hyun Sun JeonDepartment of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. jeonhs@snu.ac.kr.ORCID http://orcid.org/0000-0003-0733-3871
Seoul National University Bundang Hospital · KRSeoul National University · KR

Funding

national research foundation of korea NRF-2019R1G1A1009371seoul national university hospital 21-2021-287
6 · The paper itself

Abstract

backgroundConjunctival myeloid sarcoma (MS) as an isolated presentation of acute myeloid leukemia (AML) relapse is rare. Here, we report a case of unilateral conjunctival MS revealed as a sign of AML relapse. CASE PRESENTATION: A 50-year-old man with a history of AML in remission visited our clinic presenting with a left conjunctival injection persisting for 1 month. Diffuse subconjunctival thickening with conjunctival vascular engorgement was observed. Ultrasound biomicroscopy revealed a hyper-reflective, thickened conjunctiva in his left eye. During the incisional biopsy, the lesion was strongly attached to the underlying sclera; histopathologic examination revealed infiltration of leukemic blasts. The relapse of AML was confirmed by a successive bone marrow biopsy. The ocular lesion disappeared after allogeneic peripheral blood stem cell transplantation (PBSCT) and concomitant salvage radiotherapy on the left eye. The patient has remained in remission for 3 years after allogeneic PBSCT.

conclusionsIncidental conjunctival lesions can indicate AML relapse in patients treated earlier for AML. An ophthalmologist may have a role in the early detection of AML when a patient presents with an atypical conjunctival lesion.

Indexed as

Conjunctival NeoplasmsHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteSarcoma, MyeloidConjunctivaHumansMaleMiddle AgedAcute myeloid leukemiaCase reportConjunctival myeloid sarcomaRadiotherapyRelapse

Identifiers

PMID35144564
PMCPMC8832649
OpenAlexW4211104777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.