Evidence map›Paper›PMID 35143973›Full record

ArticleNeuroImage2022

Integrating

Abigail T J Cember, Neil E Wilson, Laurie J Rich, Puneet Bagga, Ravi Prakash Reddy Nanga, Sophia Swago, Anshuman Swain, Deepa Thakuri, Mark Elliot, Mitchell D Schnall and 2 more

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Human Brain Deuterium Metabolic Imaging at 7 T: Impact of Different [6,6'-Journal of magnetic resonance imaging : JMRI · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Nature biomedical engineering · 2023
    Article
  12. Review
  13. Reproducibility of 3D MRSI for imaging human brain glucose metabolism using direct (medRxiv : the preprint server for health sciences · 2023
    Article
  14. Mapping endocrine networks by stable isotope tracing.Current opinion in endocrine and metabolic research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Abigail T J CemberDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Graduate Group in Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Neil E WilsonDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Siemens Medical Solutions USA, Malvern, PA, USA.
Laurie J RichDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Puneet BaggaDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN, USA.
Ravi Prakash Reddy NangaDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Sophia SwagoDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Anshuman SwainDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Deepa ThakuriDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Mark ElliotDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Mitchell D SchnallDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
John A DetreDepartment of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Ravinder ReddyDepartment of Radiology, Center for Advanced Metabolic Imaging in Precision Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address: krr@pennmedicine.upenn.edu.
University of Pennsylvania · USMedical Solutions · GBSt. Jude Children's Research Hospital · US

Funding

Training and DisseminationP41EB015893 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2012 to 2019
$11.3M
High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Training Program in Biomedical Imaging and Information SciencesT32EB009384 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C, IVES, ZACHARY · 2009 to 2023
$4.0M
Imaging of glutamatergic system changes in Alzheimer's disease in vivoR01AG063869 · NIA · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2020 to 2024
$3.0M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
A Novel Method for Glutamate ImagingR01NS087516 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2014 to 2018
$1.7M
NIA NIH HHS R01 AG063869NIBIB NIH HHS P41 EB015893NIBIB NIH HHS P41 EB029460NIBIB NIH HHS T32 EB009384NIBIB NIH HHS T32 EB020087NINDS NIH HHS R01 NS087516
6 · The paper itself

Abstract

In the technique presented here, dubbed 'qMRS', we quantify the change in

Indexed as

GlucoseMagnetic Resonance ImagingDeuteriumHumansMagnetic Resonance SpectroscopyProton Magnetic Resonance SpectroscopyDeuteriumGlucoseChemical shift imagingDeuteriumGlucoseGlutamateMetabolismMRISpectroscopy

Identifiers

PMID35143973
PMCPMC9166154
OpenAlexW4210831627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.