ArticleMolecular biology and evolution2022
Comparative Genomics Elucidates the Origin of a Supergene Controlling Floral Heteromorphism.
Article in Molecular biology and evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed.
- Distinct genomic architectures but the same gene underlie the convergent evolution of a plant supergene.Science advances · 2026Article
- Recombination suppression in plant adaptation and speciation.The New phytologist · 2026Review
- Plant transcriptome data mining identified twenty-two putative novel taxa in the family Closteroviridae.Archives of virology · 2026Article
- Chromosome-level genome assembly and annotation of the endangered plant Primula kwangtungensis (Primulaceae).Scientific data · 2026Article
- Genomic architecture and evolution of heterostyly: new insights from Cordia subcordata (Boraginaceae).Molecular biology and evolution · 2026Article
- Pan-S-locus analysis reveals insights into the origin and evolution of self-incompatibility in the orange subfamily.Genome biology · 2025Article
- Heterostylous plants in an era of global change: a review on the consequences of habitat loss and fragmentation.AoB PLANTS · 2025Review
- Genomic Patterns of Loss of Distyly and Polyploidization in Primroses.Molecular biology and evolution · 2025Article
- The Genomic Basis of the Tristylous Floral Polymorphism: Evidence for a Role of Gene Duplications in a Region of Restricted Recombination.Molecular biology and evolution · 2025Article
- Copy number variation contributes to parallel local adaptation in an invasive plant.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genetic transformation ofFrontiers in plant science · 2025Article
- Rapid detection of RNase-based self-incompatibility in Lysimachia monelli (Primulaceae).American journal of botany · 2025Article
- Unveiling the Genome-Wide Consequences of Range Expansion and Mating System Transitions in Primula vulgaris.Genome biology and evolution · 2024Article
- Probing of plant transcriptomes reveals the hidden genetic diversity of the family Secoviridae.Archives of virology · 2024Article
- PfPIN5 promotes style elongation by regulating cell length in Primula forbesii Franch.Annals of botany · 2024Article
- Genomic analyses elucidateEcology and evolution · 2024Article
- Convergent evolutionary patterns of heterostyly across angiosperms support the pollination-precision hypothesis.Nature communications · 2024Article
- Phylogenomics of the pantropical Connaraceae: revised infrafamilial classification and the evolution of heterostyly.Plant systematics and evolution = Entwicklungsgeschichte und Systematik der Pflanzen · 2024Article
- Subgenome dominance shapes novel gene evolution in the decaploid pitcher plant Nepenthes gracilis.Nature plants · 2023Article
- Genome sequencing reveals the genetic architecture of heterostyly and domestication history of common buckwheat.Nature plants · 2023Article
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11 authors.
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Abstract
Supergenes are nonrecombining genomic regions ensuring the coinheritance of multiple, coadapted genes. Despite the importance of supergenes in adaptation, little is known on how they originate. A classic example of supergene is the S locus controlling heterostyly, a floral heteromorphism occurring in 28 angiosperm families. In Primula, heterostyly is characterized by the cooccurrence of two complementary, self-incompatible floral morphs and is controlled by five genes clustered in the hemizygous, ca. 300-kb S locus. Here, we present the first chromosome-scale genome assembly of any heterostylous species, that of Primula veris (cowslip). By leveraging the high contiguity of the P. veris assembly and comparative genomic analyses, we demonstrated that the S-locus evolved via multiple, asynchronous gene duplications and independent gene translocations. Furthermore, we discovered a new whole-genome duplication in Ericales that is specific to the Primula lineage. We also propose a mechanism for the origin of S-locus hemizygosity via nonhomologous recombination involving the newly discovered two pairs of CFB genes flanking the S locus. Finally, we detected only weak signatures of degeneration in the S locus, as predicted for hemizygous supergenes. The present study provides a useful resource for future research addressing key questions on the evolution of supergenes in general and the S locus in particular: How do supergenes arise? What is the role of genome architecture in the evolution of complex adaptations? Is the molecular architecture of heterostyly supergenes across angiosperms similar to that of Primula?
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