Evidence map›Paper›PMID 35143583›Full record

ArticlePloS one2022

Quantifying rural disparity in healthcare utilization in the United States: Analysis of a large midwestern healthcare system.

Akua Nuako, Jingxia Liu, Giang Pham, Nina Smock, Aimee James, Timothy Baker, Laura Bierut, Graham Colditz, Li-Shiun Chen

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Addressing Access Barriers in Rural America: A Mixed-Methods Study of Wisconsin's Family Resource Centers.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026
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  18. The role of veterans hospitals in Taiwan's medically underserved areas.Journal of the Chinese Medical Association : JCMA · 2025
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  19. Article
  20. Rural nonprofit hospital community benefit and financial assistance spending: A call for greater reporting transparency.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akua NuakoDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States America.ORCID 0000-0002-3221-5052
Jingxia LiuAlvin J. Siteman Cancer Center at Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO, United States America.
Giang PhamDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States America.
Nina SmockDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States America.
Aimee JamesAlvin J. Siteman Cancer Center at Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO, United States America.
Timothy BakerDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, United States America.
Laura BierutDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States America.
Graham ColditzAlvin J. Siteman Cancer Center at Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO, United States America.ORCID 0000-0002-7307-0291
Li-Shiun ChenDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States America.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Testing Relapse Recovery Intervention ComponentsP01CA180945 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI COOK, JESSICA MEGAN · 2014 to 2023
$23.0M
Transforming The Treatment of Tobacco Use in Health Care: Seizing The Potential of the Electronic Health Record to Deliver Comprehensive Chronic Care Treatment for SmokingR35CA197573 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MICHAEL C FIORE · 2015 to 2026
$10.7M
Genetically Informed Smoking Cessation TrialR01DA038076 · NIDA · WASHINGTON UNIVERSITY · PI CHEN, LI-SHIUN · 2014 to 2018
$3.3M
Nicotine Dependence to Smoking Cessation: Sequencing Common and Rare VariantsR01DA036583 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2014 to 2017
$3.0M
NCATS NIH HHS UL1 TR002345NCI NIH HHS P01 CA180945NCI NIH HHS P30 CA091842NCI NIH HHS R35 CA197573NIDA NIH HHS R01 DA036583NIDA NIH HHS R01 DA038076
6 · The paper itself

Abstract

purposeThe objective of this study is to identify how predisposing characteristics, enabling factors, and health needs are jointly and individually associated with epidemiological patterns of outpatient healthcare utilization for patients who already interact and engage with a large healthcare system.

methodsWe retrospectively analyzed electronic medical record data from 1,423,166 outpatient clinic visits from 474,674 patients in a large healthcare system from June 2018-March 2019. We evaluated patients who exclusively visited rural clinics versus patients who exclusively visited urban clinics using Chi-square tests and the generalized estimating equation Poisson regression methodology. The outcome was healthcare use defined by the number of outpatient visits to clinics within the healthcare system and independent variables included age, gender, race, ethnicity, smoking status, health status, and rural or urban clinic location. Supplementary analyses were conducted observing healthcare use patterns within rural and urban clinics separately and within primary care and specialty clinics separately.

findingsPatients in rural clinics vs. urban clinics had worse health status [χ2 = 935.1, df = 3, p<0.0001]. Additionally, patients in rural clinics had lower healthcare utilization than patients in urban clinics, adjusting for age, race, ethnicity, gender, smoking, and health status [2.49 vs. 3.18 visits, RR = 0.61, 95%CI = (0.55,0.68), p<0.0001]. Further, patients in rural clinics had lower utilization for both primary care and specialty care visits.

conclusionsWithin the large healthcare system, patients in rural clinics had lower outpatient healthcare utilization compared to their urban counterparts despite having potentially elevated health needs reflected by a higher number of unique health diagnoses documented in their electronic health records after adjusting for multiple factors. This work can inform future studies exploring the roots and ramifications of rural-urban healthcare utilization differences and rural healthcare disparities.

Indexed as

AdultAgedCross-Sectional StudiesDelivery of Health CareFemaleHealthcare DisparitiesHumansMaleMiddle AgedMidwestern United StatesPatient Acceptance of Health CarePoisson DistributionRetrospective StudiesRisk FactorsRural HealthUrban Health

Identifiers

PMID35143583
PMCPMC8830640

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.