Evidence map›Paper›PMID 35143305›Full record

ArticleScience (New York, N.Y.)2022

CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells.

Dan Liu, Lihui Duan, Lauren B Rodda, Erick Lu, Ying Xu, Jinping An, Longhui Qiu, Fengchun Liu, Mark R Looney, Zhiyong Yang and 4 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
  2. Article
  3. CD97/Cells · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Adhesion G protein-coupled receptors.Pharmacological reviews · 2026
    Review
  9. Article
  10. Review
  11. ABCC1 protects skin dendritic cells from FITC-induced toxicity by efflux and extracellular glutathione buffering.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Dan LiuHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-5601-8053
Lihui DuanHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
Lauren B RoddaHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0001-7763-8166
Erick LuHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0001-8175-5146
Ying XuHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
Jinping AnHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
Longhui QiuDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Fengchun LiuDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-0775-0608
Mark R LooneyDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-0241-9190
Zhiyong YangCardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-0589-6224
Christopher D C AllenCardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-1879-9047
Zhongmei LiJ. David Gladstone Institutes, San Francisco, CA 94158, USA.
Alexander MarsonDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-2734-5776
Jason G CysterHoward Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-4735-9745
Howard Hughes Medical Institute · USUniversity of California, San Francisco · USGladstone Institutes · US

Funding

MOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0M
B LYMPHOCYTE MIGRATION AND HOMEOSTASISR01AI040098 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jason G Cyster · 1997 to 2026
$7.0M
Beta Lymphocyte Migration and HomeostasisR37AI040098 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 2002 to 2011
$3.2M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI040098NIAID NIH HHS R37 AI040098NIAID NIH HHS T32 AI007334
6 · The paper itself

Abstract

Dendritic cells (DCs) are crucial for initiating adaptive immune responses. However, the factors that control DC positioning and homeostasis are incompletely understood. We found that type-2 conventional DCs (cDC2s) in the spleen depend on Gα

Indexed as

ActinsAnimalsAntigen PresentationAntigensBlood CirculationCD55 AntigensCell MovementDendritic CellsErythrocytesGTP-Binding Protein alpha Subunits, G12-G13HomeostasisInterferon Regulatory Factor-4Interferon Regulatory FactorsLigandsMiceReceptors, G-Protein-CoupledActinsAdgre5 protein, mouseAntigensCD55 AntigensGTP-Binding Protein alpha Subunits, G12-G13Interferon Regulatory Factor-4Interferon Regulatory FactorsLigandsReceptors, G-Protein-Coupled

Identifiers

PMID35143305
PMCPMC9310086
OpenAlexW4210998457

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.