Evidence map›Paper›PMID 35143286›Full record

ArticleThe British journal of radiology2022

COPD identification and grading based on deep learning of lung parenchyma and bronchial wall in chest CT images.

Lin Zhang, Beibei Jiang, Hendrik Joost Wisselink, Rozemarijn Vliegenthart, Xueqian Xie

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Automatic Body Region Classification in CT Scans Using Deep Learning.Journal of imaging informatics in medicine · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
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  9. Article
  10. Diagnosis and Severity Assessment of COPD Based on Machine Learning of Chest CT Images.International journal of chronic obstructive pulmonary disease · 2025
    Article
  11. Article
  12. Review
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  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lin ZhangRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Beibei JiangRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hendrik Joost WisselinkRadiology Department, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Rozemarijn VliegenthartRadiology Department, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Xueqian XieRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-6669-0097
Shanghai Jiao Tong University · CNUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChest CT can display the main pathogenic factors of chronic obstructive pulmonary disease (COPD), emphysema and airway wall remodeling. This study aims to establish deep convolutional neural network (CNN) models using these two imaging markers to diagnose and grade COPD.

methodsSubjects who underwent chest CT and pulmonary function test (PFT) from one hospital (

resultsIn the test cohort, CNN achieved an area under the curve of 0.899 (95%CI: 0.853-0.935) to determine the existence of COPD, and an accuracy of 81.7% (76.2-86.7%), which was significantly higher than the accuracy 68.1% (61.6%-74.2%) using quantitative CT method (

conclusionCNN can identify emphysema and airway wall remodeling on CT images to infer lung function and determine the existence and severity of COPD. It provides an alternative way to detect COPD using the extensively available chest CT. ADVANCES IN KNOWLEDGE: CNN can identify the main pathological changes of COPD (emphysema and airway wall remodeling) based on CT images, to infer lung function and determine the existence and severity of COPD. CNN reached an area under the curve of 0.853 to determine the existence of COPD in the external test cohort. The CNN approach provides an alternative and effective way for early detection of COPD using extensively used chest CT, as an important alternative to pulmonary function test.

Indexed as

Deep LearningEmphysemaPulmonary Disease, Chronic ObstructivePulmonary EmphysemaHumansLungRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID35143286
PMCPMC10993953
OpenAlexW4211081083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.