Evidence map›Paper›PMID 35143047›Full record

ArticleThe EMBO journal2022

Fluidity is the way to life: lipid phase separation in bacterial membranes.

Marc Bramkamp

Open access · bronzeAbstract readComment
In one paragraph

Article in The EMBO journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Journal of bacteriology · 2026
    Article
  2. The Evolution of Lipids from Solvents to Substrates.Annual review of biophysics · 2026
    Review
  3. Article
  4. Article
  5. Sphingolipid-mediated vesiculation in multidrug-resistantApplied and environmental microbiology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function.Cold Spring Harbor perspectives in biology · 2023
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Marc BramkampInstitute for General Microbiology, Christian-Albrechts-University Kiel, Kiel, Germany.ORCID 0000-0002-7704-3266
Christian-Albrechts-Universität zu Kiel · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A hallmark of biological membranes is the dynamic localization of lipids and proteins. Lipids respond to temperature reduction below a critical point with phase separation, and poikilothermic animals and also bacteria adapt their lipid content to prevent gel phase formation in membranes. In a new study, Gohrbandt et al (2022) show that reduced membrane fluidity in bacterial cells causes reversible phase separation without membrane rupture in vivo, highlighting the physical robustness of biological membranes.

Indexed as

BacteriaMembrane FluidityAnimalsCell MembraneLipidsMembranesLipids

Identifiers

PMID35143047
PMCPMC8886535
OpenAlexW4210966177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.