Evidence map›Paper›PMID 35142867›Full record

ArticleRheumatology international2022

Toll-like receptor-7 activation in CD8+ T cells modulates inflammatory mediators in patients with rheumatoid arthritis.

Nitish Swain, Archana Tripathy, Prasanta Padhan, Sunil K Raghav, Bhawna Gupta

Abstract read
PubMed Publisher
In one paragraph

Article in Rheumatology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Unraveled role of TLR7-mediated interferon signaling activation in COVID-19.Frontiers in cellular and infection microbiology · 2025
    Review
  7. What role of the cGAS-STING pathway plays in chronic pain?Frontiers in molecular neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nitish SwainDisease Biology Laboratory, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar, Odisha, 751024, India.ORCID 0000-0002-6931-9285
Archana TripathyDisease Biology Laboratory, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar, Odisha, 751024, India.ORCID 0000-0001-6518-2114
Prasanta PadhanDepartment of Rheumatology, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India.ORCID 0000-0002-2545-9032
Sunil K RaghavLaboratory of Immuno-Genomics and Systems Biology, Institute of Life Sciences, Bhubaneswar, Odisha, India.ORCID 0000-0001-9913-4241
Bhawna GuptaDisease Biology Laboratory, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Bhubaneswar, Odisha, 751024, India. bhawna.gupta@kiitbiotech.ac.in.ORCID 0000-0001-8476-3942
KIIT University · INAll India Institute of Medical Sciences Bhubaneswar · INInstitute of Life Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is an autoimmune disorder of unknown etiology with aberrant immunological responses leading to inflammation, swelling and pain of the joints. CD8

Indexed as

Arthritis, RheumatoidToll-Like Receptor 7CD8-Positive T-LymphocytesCytokinesHumansInflammation MediatorsRNA, MessengerToll-Like ReceptorsCytokinesInflammation MediatorsRNA, MessengerTLR7 protein, humanToll-Like Receptor 7Toll-Like ReceptorsCD8+ T cellsIMQRheumatoid arthritisTLR7Tristetraprolin

Identifiers

PMID35142867
OpenAlexW4210990859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.