ReviewNeural regeneration research2022
Alerting effects of light in healthy individuals: a systematic review and meta-analysis.
Review in Neural regeneration research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Pooled it
- Reducing Test Anxiety: A Randomized Controlled Pilot Study of Evening Bright Light Exposure in University Students.Depression and anxiety · 2025Trial
- Impact of repeated morning bright white light exposures on attention in a simulated office environment.Scientific reports · 2023Trial
- Cortical excitability is affected by light exposure - Distinct effects in adolescents and young adults.Neurobiology of sleep and circadian rhythms · 2026Article
- Outdoor light at night and neuropsychiatric symptoms in dementia.GeroScience · 2026Article
- Goal-directed human factor experiment on the non-visual effect of luminous environment on indoor exercise.Scientific reports · 2026Article
- Dysfunctional circadian-driven dynamics in gut microbiota and tumor microenvironment.Gut microbes · 2025Review
- The Impact of Lighting Conditions on Users' Alertness and Working Memory in Confined Spaces.PsyCh journal · 2025Article
- Article
- Moral decision-making at night and the impact of night work with blue-enriched white light or warm white light: a counterbalanced crossover study.Annals of medicine · 2024Article
- Towards an evidence-based integrative lighting score: a proposed multi-level approach.Annals of medicine · 2024Review
- Multimodal in-vehicle lighting system increases daytime light exposure and alertness in truck drivers under Arctic winter conditions.Scientific reports · 2024Article
- A Comprehensive Overview of the Neural Mechanisms of Light Therapy.Neuroscience bulletin · 2024Review
- Evaluation of the effects of blue-enriched white light on cognitive performance, arousal, and overall appreciation of lighting.Frontiers in public health · 2024Article
- The role of arousal in maintaining the relationship between insomnia and gastrointestinal conditions.Translational gastroenterology and hepatology · 2024Review
- Article
- Light as a Modulator of Non-Image-Forming Brain Functions-Positive and Negative Impacts of Increasing Light Availability.Clocks & sleep · 2023Review
- Effects of Ambient Illuminance on Explicit and Implicit Altruism: The Mediation Roles of Perceived Anonymity and Satisfaction with Light.International journal of environmental research and public health · 2022Article
- Bright light therapy-induced improvements of mood, cognitive functions and cerebellar functional connectivity in subthreshold depression: A randomized controlled trial.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light plays an essential role in psychobiological and psychophysiological processes, such as alertness. The alerting effect is influenced by light characteristics and the timing of interventions. This meta-analysis is the first to systematically review the effect of light intervention on alertness and to discuss the optimal protocol for light intervention. In this meta-analysis, registered at PROSPERO (Registration ID: CRD42020181485), we conducted a systematic search of the Web of Science, PubMed, and PsycINFO databases for studies published in English prior to August 2021. The outcomes included both subjective and objective alertness. Subgroup analyses considered a variety of factors, such as wavelength, correlated color temperature (CCT), light illuminance, and timing of interventions (daytime, night-time, or all day). Twenty-seven crossover studies and two parallel-group studies were included in this meta-analysis, with a total of 1210 healthy participants (636 (52%) male, mean age 25.62 years). The results revealed that light intervention had a positive effect on both subjective alertness (standardized mean difference (SMD) = -0.28, 95% confidence interval (CI): -0.49 to -0.06, P = 0.01) and objective alertness in healthy subjects (SMD = -0.34, 95% CI: -0.68 to -0.01, P = 0.04). The subgroup analysis revealed that cold light was better than warm light in improving subjective alertness (SMD = -0.37, 95% CI: -0.65 to -0.10, P = 0.007, I
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.