Evidence map›Paper›PMID 35142579›Full record

ArticleInnate immunity2022

Protective effects of the notoginsenoside R1 on acute lung injury by regulating the miR-128-2-5p/Tollip signaling pathway in rats with severe acute pancreatitis.

Ju He, Ming-Wei Liu, Zhi-Yi Wang, Rong-Jie Shi

Open access · goldAbstract read
In one paragraph

Article in Innate immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. The Role of MicroRNAs in Pancreatitis Development and Progression.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ju HeDepartment of Gastrointestinal Surgery, First Affiliated Hospital of Dali University, Dali City, China.
Ming-Wei LiuDepartment of Emergency, 36657The First Hospital Affiliated of Kunming Medical University, Kunming, China.
Zhi-Yi WangDepartment of Gastrointestinal Surgery, First Affiliated Hospital of Dali University, Dali City, China.
Rong-Jie ShiDepartment of Gastroenterology, First Affiliated Hospital of Dali University, Dali City, China.ORCID 0000-0001-6954-6974
Dali University · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Notoginsenoside R1 (NG-R1), the extract and the main ingredient of

Indexed as

Acute Lung InjuryHMGB1 ProteinMicroRNAsPancreatitisAcute DiseaseAnimalsGinsenosidesIntercellular Adhesion Molecule-1Interleukin-6Intracellular Signaling Peptides and ProteinsMyeloid Differentiation Factor 88NF-kappa BNF-KappaB Inhibitor alphaRatsSignal TransductionToll-Like Receptor 4GinsenosidesHMGB1 ProteinIntercellular Adhesion Molecule-1Interleukin-6Intracellular Signaling Peptides and ProteinsMicroRNAsMIRN128 microRNA, ratMyeloid Differentiation Factor 88NF-kappa BNF-KappaB Inhibitor alphanotoginsenoside R1tollip protein, ratToll-Like Receptor 4Tumor Necrosis Factor-alphaacute lung injurymiR-128-2-5pNotoginsenoside R1pancreatitisratsToll interacting protein

Identifiers

PMID35142579
PMCPMC8841636
OpenAlexW4210948874

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.