Evidence map›Paper›PMID 35142398›Full record

ArticleMagnetic resonance in medicine2022

Intracardiac MR imaging (ICMRI) guiding-sheath with amplified expandable-tip imaging and MR-tracking for navigation and arrythmia ablation monitoring: Swine testing at 1.5 and 3T.

Ehud J Schmidt, Gregory Olson, Junichi Tokuda, Akbar Alipour, Ronald D Watkins, Eric M Meyer, Hassan Elahi, William G Stevenson, Jeffrey Schweitzer, Charles L Dumoulin and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Ehud J SchmidtMedicine (Cardiology), Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-5792-2087
Gregory OlsonCardiac Arrhythmia and Heart Failure Division, Abbott Laboratories, Minnetonka, Minnesota, USA.
Junichi TokudaRadiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Akbar AlipourMedicine (Cardiology), Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-7981-6808
Ronald D WatkinsRadiology, Stanford University, Stanford, California, USA.
Eric M MeyerMedicine (Cardiology), Johns Hopkins University, Baltimore, Maryland, USA.
Hassan ElahiMedicine (Cardiology), Johns Hopkins University, Baltimore, Maryland, USA.
William G StevensonCardiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Jeffrey SchweitzerCardiac Arrhythmia and Heart Failure Division, Abbott Laboratories, Minnetonka, Minnesota, USA.
Charles L DumoulinRadiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Thomas JohnsonCatapult Product Development, Waltham, Massachusetts, USA.
Aravindan KolandaiveluMedicine (Cardiology), Johns Hopkins University, Baltimore, Maryland, USA.
Wolfgang LoewRadiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Henry R HalperinMedicine (Cardiology), Johns Hopkins University, Baltimore, Maryland, USA.
Johns Hopkins University · USAbbott (United States) · USBrigham and Women's Hospital · USCincinnati Children's Hospital Medical Center · USCatapult · USUniversity Radiology · US

Funding

Boston Biomedical Innovation CenterU54HL119145 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLAN, DAVID E., LOSCALZO, JOSEPH · 2013 to 2021
$18.8M
ULTRASOUND THERAPY DELIVERY THROUGH INTACT SKULLU41RR019703 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLBY, ALEXANDRA J · 2005 to 2009
$17.2M
Improved Targeting and Assessment of Electrophysiology InterventionR01HL094610 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HALPERIN, HENRY R · 2009 to 2018
$15.5M
IMAGE GUIDED THERAPY CENTERP41RR019703 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI JOLESZ, FERENC A · 2010 to 2011
$8.6M
Open Software Platform for Data-Driven Image-Guided Robotic InterventionsR01EB020667 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI DIAZ-MERCADO, YANCY, KRIEGER, AXEL · 2015 to 2024
$4.1M
Atrial fibrillation ablation assessment and guidance using native-contrast T1 weighted MRIR01HL157259 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KOLANDAIVELU, ARAVINDAN · 2021 to 2025
$3.9M
Physician Assistance Technology in Image-guided Robotic Intervention of ProstateR01EB030539 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI HATA, NOBUHIKO, ZHANG, HAICHONG · 2021 to 2024
$2.7M
NCRR NIH HHS P41 RR019703NCRR NIH HHS U41 RR019703NHLBI NIH HHS R01 HL094610NHLBI NIH HHS R01 HL157259NHLBI NIH HHS U54 HL119145NIBIB NIH HHS R01 EB020667NIBIB NIH HHS R01 EB030539
6 · The paper itself

Abstract

purposeDevelop a deflectable intracardiac MR imaging (ICMRI) guiding-sheath to accelerate imaging during MR-guided electrophysiological (EP) interventions for radiofrequency (500 kHz) ablation (RFA) of arrythmia. Requirements include imaging at three to five times surface-coil SNR in cardiac chambers, vascular insertion, steerable-active-navigation into cardiac chambers, operation with ablation catheters, and safe levels of MR-induced heating.

methodsICMRI's 6 mm outer-diameter (OD) metallic-braided shaft had a 2.6 mm OD internal lumen for ablation-catheter insertion. Miniature-Baluns (MBaluns) on ICMRI's 1 m shaft reduced body-coil-induced heating. Distal section was a folded "star"-shaped imaging-coil mounted on an expandable frame, with an integrated miniature low-noise-amplifier overcoming cable losses. A handle-activated movable-shaft expanded imaging-coil to 35 mm OD for imaging within cardiac-chambers. Four MR-tracking micro-coils enabled navigation and motion-compensation, assuming a tetrahedron-shape when expanded. A second handle-lever enabled distal-tip deflection. ICMRI with a protruding deflectable EP catheter were used for MR-tracked navigation and RFA using a dedicated 3D-slicer user-interface. ICMRI was tested at 3T and 1.5T in swine to evaluate (a) heating, (b) cardiac-chamber access, (c) imaging field-of-view and SNR, and (d) intraprocedural RFA lesion monitoring.

resultsThe 3T and 1.5T imaging SNR demonstrated >400% SNR boost over a 4 × 4 × 4 cm

conclusionICMRI assisted EP-catheter navigation to difficult targets and accelerated RFA monitoring.

Indexed as

Catheter AblationMagnetic Resonance ImagingAnimalsArrhythmias, CardiacEquipment DesignHeart AtriaSwineacute RF lesion imagingcardiac electrophysiologyinterventional MRI

Identifiers

PMID35142398
PMCPMC8957513
OpenAlexW4211180564

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.