Evidence map›Paper›PMID 35142371›Full record

ReviewDevelopmental medicine and child neurology2022

Effects of voluntary exercise on muscle structure and function in cerebral palsy.

Noelle G Moreau, Richard L Lieber

Open access · bronzeAbstract readReview
In one paragraph

Review in Developmental medicine and child neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Noelle G MoreauDepartment of Physical Therapy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Richard L LieberShirley Ryan AbilityLab and Department of Physiology, Northwestern University, Hines VA Medical Center, Chicago, Illinois, USA.ORCID 0000-0002-7203-4520
Louisiana State University Health Sciences Center New Orleans · USNorthwestern University · US

Funding

Short-Burst Interval Treadmill Training to Improve Community Walking Activity and Mobility in Cerebral PalsyR01HD098270 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI BJORNSON, KRISTIE F, MOREAU, NOELLE G · 2019 to 2024
$2.8M
Power Training Combined with Interval Treadmill Training to Improve Walking Activity in Cerebral PalsyR01HD091089 · NICHD · LSU HEALTH SCIENCES CENTER · PI MOREAU, NOELLE G · 2018 to 2022
$2.5M
Muscle Biological and Biomechanical Response in Cerebral PalsyR01AR057393 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L. · 2010 to 2014
$1.7M
Skeletal Muscle Injury: Mechanism Prevention &TreatmentR01AR040050 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L · 1989 to 2007
$1.6M
Intraoperative Optimization and Validation of Musculoskeletal ReconstructionI01RX002462 · VA · EDWARD HINES JR VA HOSPITAL · PI LIEBER, RICHARD L. · 2018 to 2025
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NIAMS NIH HHS R01 AR040050NIAMS NIH HHS R01 AR057393NICHD NIH HHS R01 HD091089NICHD NIH HHS R01 HD098270RRD VA I01 RX002462
6 · The paper itself

Abstract

Skeletal muscles are required for functional movement and force production. While it is clear that cerebral palsy (CP) results in loss of muscle strength and bodily function, and that much of this loss is caused by injury to the central nervous system, muscle is a very plastic tissue that is also dramatically affected. In many studies, it is assumed that voluntary exercise will cause the muscle to respond in the same way that typically developing muscle does, but there are scarce data demonstrating that this is true. The purpose of this review is to briefly describe muscle architectural adaptation to various forms of exercise with specific reference to voluntary exercise performed in children with CP. Exercise itself is not generic but can vary by intensity, duration, and the exact nature of the muscle length change and velocity imposed during the exercise. Our goal is to stimulate discussion in this area by pointing out salient experimental variables and, ultimately, to improve activity and participation in children with CP.

Indexed as

Cerebral PalsyChildExerciseHumansMovementMuscle, SkeletalMuscle Strength

Identifiers

PMID35142371
PMCPMC9086177
OpenAlexW4210966156

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.